The International Maritime Organization (IMO) has proposed various safety standards which ship engineers are required to follow. It is therefore necessary to consider a ship's safety during its initial design stages. The larger ships such as large cargo carriers require strict safety standards. With larger vessels such as these, the IMO safety standards stipulate the need for a vessel to demonstrate high maneuverability - this may be achieved with a twin-screw ship. Demand for twin-screw ships will therefore increase in near future. Thus, when it comes to the maneuverability of a twin-screw ship, the existing research leaves a lot to be desired as it primarily focuses on container ships. For these reasons, it is crucial that thorough research is performed on the maneuverability of other styles of twin-screw ships, such as naval combatants.Most studies on the manoeuvrability of twin-screw ships have focused on container ships as there is an abundance of existing data available for them. However, container ships tend to have less manoeuvring problems compared to other types of ships. Thus, when it comes to the manoeuvrability of a twin-screw ship, the existing research leaves a lot to be desired as it primarily focuses on container ships. For these reasons, it is crucial that thorough research is performed on the manoeuvrability of other types of twin-screw ships, such as naval combatants.The main goal of this research is to assess the manoeuvrability of the twin-screw naval combatant ship the DTMB 5415 using Computational Fluid Dynamics (CFD) and MATLAB.In this research, Star-CCM+ is used as a RANS solver to measure the hydrodynamic forces and moments on the twin-screw and derive the hydrodynamic derivatives. To validate the simulated results, a comparison is made against the existing experimental data from the published literature. Following this, MATLAB will be used to predict the manoeuvrability of the vessel in question such as its turning ability and course changing ability. A Mathematical Modelling Group (MMG) model is then used to predict the individual hydrodynamic forcesof the propeller and hull.