XRT: Extraction of quantitative structural descriptors from solid pharmaceutical products

Frederik J. S. Doerr, Alastair J. Florence

Research output: Contribution to conferencePresentation/Speech

30 Downloads (Pure)


In this project we demonstrate the use of x-ray tomography for the quantification of structural descriptors from two selected solid pharmaceutical products: single formulated particles and a commercial Ibuprofen capsule. In particular, we demonstrate the application of image processing strategies for noise reduction, image segmentation and the extraction of quantitative structural descriptors. Information on the sample’s solid state properties can be used to evaluate the manufacturing process and allows a prediction of the solid performance for subsequent processing steps or after administration to the patient.
Original languageEnglish
Publication statusPublished - 17 Apr 2018
EventBruker Micro-CT User Meeting - Ghent, Belgium
Duration: 16 Apr 201819 Apr 2018


ConferenceBruker Micro-CT User Meeting
Internet address


  • X-ray tomography
  • pharmaceutics
  • pellets
  • capsules
  • characterisation
  • image analysis


Dive into the research topics of 'XRT: Extraction of quantitative structural descriptors from solid pharmaceutical products'. Together they form a unique fingerprint.

Cite this