What is the initiation step of the Grubbs-Hoveyda olefin metathesis catalyst?

Ian W. Ashworth, Ian H. Hillier, David J. Nelson, Jonathan M. Percy, Mark A. Vincent

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Density function theory calculations reveal that the Grubbs-Hoveyda olefin metathesis pre-catalyst is activated by the formation of a complex in which the incoming alkene substrate and outgoing alkoxy ligand are both clearly associated with the ruthenium centre. The computed energies for reaction are in good agreement with the experimental values, reported here.
Original languageEnglish
Pages (from-to)5428-5430
Number of pages3
JournalChemical Communications
Issue number19
Early online date11 Apr 2011
Publication statusPublished - 21 May 2011



  • olefin metathesis
  • metathesis catalyst
  • alkene substrates
  • alkoxy ligands

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