Wet milling of mefenamic acid for seed generation: model-driven size reduction for maximizing yield

Bhavik Mehta, Cameron Brown, Niall Mitchell, Sara Ottoboni

Research output: Contribution to conferencePoster

13 Downloads (Pure)

Abstract

Introduction•Wet milling overcomes several common issues encountered with dry milling, including:
- Undesired polymorphic and amorphous transformations
- Loss of yield and process control
- Increased energy cost
• The aim of this work is to explore the region of attainable particle sizes based on the performance of a wet milling model, focusing on:
- Development of a mechanistic model from initial small-scale experiments
- Design space exploration to assess the quality attributes and suggest further experimental work with a view to make the model more robust
Original languageEnglish
Pages13-13
Number of pages1
Publication statusPublished - 16 May 2022
EventCMAC Annual Open Day 2022 - Glasgow, United Kingdom
Duration: 16 May 202218 May 2022

Conference

ConferenceCMAC Annual Open Day 2022
Country/TerritoryUnited Kingdom
CityGlasgow
Period16/05/2218/05/22

Keywords

  • wet milling
  • seed generation
  • attainable particle sizes

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