Abstract
Giovannucci enquires whether intervention studies were long enough to allow full expression of health benefits associated with high serum 25-hydroxyvitamin D (25[OH]D) concentrations. Recent meta-analyses that compared top to bottom quantiles of 25(OH)D found summary relative risks of 0·67 (95% CI: 0·59–0·75) in 16 studies of type 2 diabetes1 and of 0·66 (0·54–0·81) in eight studies of colorectal cancer.2 We plotted relative risks of diabetes and colorectal cancer occurrence reported by prospective studies against follow-up duration (figure).
Original language | English |
---|---|
Pages (from-to) | 275-276 |
Number of pages | 2 |
Journal | The Lancet Diabetes & Endocrinology |
Volume | 2 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Apr 2014 |
Keywords
- intervention studies
- vitamin D
- vitamin D deficiency
- ill health