VGLUT2 functions as a differential marker for hippocampal output neurons

Christian Wozny, Prateep Beed, Noam Nitzan, Yona Pössnecker, Benjamin R. Rost, Dietmar Schmitz

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.
LanguageEnglish
Article number337
Number of pages5
JournalFrontiers in Cellular Neuroscience
Volume12
DOIs
Publication statusPublished - 2 Oct 2018

Fingerprint

Vesicular Glutamate Transport Protein 2
Hippocampus
Neurons
Pyramidal Cells
Genes

Keywords

  • channelrhodopsin-2
  • entorhinal cortex
  • hippocampus
  • subiculum
  • synaptic transmission
  • VGLUT2

Cite this

Wozny, Christian ; Beed, Prateep ; Nitzan, Noam ; Pössnecker, Yona ; Rost, Benjamin R. ; Schmitz, Dietmar. / VGLUT2 functions as a differential marker for hippocampal output neurons. In: Frontiers in Cellular Neuroscience. 2018 ; Vol. 12.
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VGLUT2 functions as a differential marker for hippocampal output neurons. / Wozny, Christian; Beed, Prateep; Nitzan, Noam; Pössnecker, Yona; Rost, Benjamin R.; Schmitz, Dietmar.

In: Frontiers in Cellular Neuroscience, Vol. 12, 337, 02.10.2018.

Research output: Contribution to journalArticle

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T1 - VGLUT2 functions as a differential marker for hippocampal output neurons

AU - Wozny, Christian

AU - Beed, Prateep

AU - Nitzan, Noam

AU - Pössnecker, Yona

AU - Rost, Benjamin R.

AU - Schmitz, Dietmar

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KW - entorhinal cortex

KW - hippocampus

KW - subiculum

KW - synaptic transmission

KW - VGLUT2

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DO - 10.3389/fncel.2018.00337

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JO - Frontiers in Cellular Neuroscience

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