VasoTracker, a low-cost and open source pressure myograph system for vascular physiology

Penelope F. Lawton, Matthew D. Lee, Christopher D. Saunter, John M. Girkin, John G. McCarron, Calum Wilson

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Pressure myography, one of the most commonly used techniques in vascular research, measures the diameter of isolated, pressurized arteries to assess the functional activity of smooth muscle and endothelial cells. Despite the widespread adoption of this technique for assessing vascular function, there are only a small number of commercial systems and these are expensive. Here, we introduce a complete, open source pressure myograph system and analysis software, VasoTracker, that can be set-up for approximately 10% of the cost of commercial alternatives. We report on the development of VasoTracker and demonstrate its ability to assess various components of vascular reactivity. A unique feature of the VasoTracker platform is the publicly accessible website (http://www.vasotracker.com/) that documents how to assemble and use this affordable, adaptable, and expandable pressure myograph.
LanguageEnglish
Article number99
Number of pages17
JournalFrontiers in Physiology
Volume10
Issue numberFEB
DOIs
Publication statusPublished - 21 Feb 2019

Fingerprint

Blood Vessels
Pressure
Costs and Cost Analysis
Myography
Systems Analysis
Smooth Muscle Myocytes
Software
Endothelial Cells
Arteries
Research

Keywords

  • pressure myography
  • blood vessel function
  • smooth muscle
  • endothelium
  • vasodilation
  • contraction

Cite this

@article{7cefedc0fab44b36881a3f61e08b69a6,
title = "VasoTracker, a low-cost and open source pressure myograph system for vascular physiology",
abstract = "Pressure myography, one of the most commonly used techniques in vascular research, measures the diameter of isolated, pressurized arteries to assess the functional activity of smooth muscle and endothelial cells. Despite the widespread adoption of this technique for assessing vascular function, there are only a small number of commercial systems and these are expensive. Here, we introduce a complete, open source pressure myograph system and analysis software, VasoTracker, that can be set-up for approximately 10{\%} of the cost of commercial alternatives. We report on the development of VasoTracker and demonstrate its ability to assess various components of vascular reactivity. A unique feature of the VasoTracker platform is the publicly accessible website (http://www.vasotracker.com/) that documents how to assemble and use this affordable, adaptable, and expandable pressure myograph.",
keywords = "pressure myography, blood vessel function, smooth muscle, endothelium, vasodilation, contraction",
author = "Lawton, {Penelope F.} and Lee, {Matthew D.} and Saunter, {Christopher D.} and Girkin, {John M.} and McCarron, {John G.} and Calum Wilson",
year = "2019",
month = "2",
day = "21",
doi = "10.3389/fphys.2019.00099",
language = "English",
volume = "10",
journal = "Frontiers in Physiology",
issn = "1664-042X",
number = "FEB",

}

VasoTracker, a low-cost and open source pressure myograph system for vascular physiology. / Lawton, Penelope F.; Lee, Matthew D.; Saunter, Christopher D.; Girkin, John M.; McCarron, John G.; Wilson, Calum.

In: Frontiers in Physiology, Vol. 10, No. FEB, 99, 21.02.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - VasoTracker, a low-cost and open source pressure myograph system for vascular physiology

AU - Lawton, Penelope F.

AU - Lee, Matthew D.

AU - Saunter, Christopher D.

AU - Girkin, John M.

AU - McCarron, John G.

AU - Wilson, Calum

PY - 2019/2/21

Y1 - 2019/2/21

N2 - Pressure myography, one of the most commonly used techniques in vascular research, measures the diameter of isolated, pressurized arteries to assess the functional activity of smooth muscle and endothelial cells. Despite the widespread adoption of this technique for assessing vascular function, there are only a small number of commercial systems and these are expensive. Here, we introduce a complete, open source pressure myograph system and analysis software, VasoTracker, that can be set-up for approximately 10% of the cost of commercial alternatives. We report on the development of VasoTracker and demonstrate its ability to assess various components of vascular reactivity. A unique feature of the VasoTracker platform is the publicly accessible website (http://www.vasotracker.com/) that documents how to assemble and use this affordable, adaptable, and expandable pressure myograph.

AB - Pressure myography, one of the most commonly used techniques in vascular research, measures the diameter of isolated, pressurized arteries to assess the functional activity of smooth muscle and endothelial cells. Despite the widespread adoption of this technique for assessing vascular function, there are only a small number of commercial systems and these are expensive. Here, we introduce a complete, open source pressure myograph system and analysis software, VasoTracker, that can be set-up for approximately 10% of the cost of commercial alternatives. We report on the development of VasoTracker and demonstrate its ability to assess various components of vascular reactivity. A unique feature of the VasoTracker platform is the publicly accessible website (http://www.vasotracker.com/) that documents how to assemble and use this affordable, adaptable, and expandable pressure myograph.

KW - pressure myography

KW - blood vessel function

KW - smooth muscle

KW - endothelium

KW - vasodilation

KW - contraction

UR - http://www.vasotracker.com

UR - https://github.com/VasoTracker/VasoTracker

U2 - 10.3389/fphys.2019.00099

DO - 10.3389/fphys.2019.00099

M3 - Article

VL - 10

JO - Frontiers in Physiology

T2 - Frontiers in Physiology

JF - Frontiers in Physiology

SN - 1664-042X

IS - FEB

M1 - 99

ER -