Using the dendritic polymer PAMAM to form gold nanoparticles in the protein cage thermosome

Martin G. Nussbaumer; Christoph Bisig; Nico Bruns

doi:10.1039/c6cc04739d

Using the dendritic polymer PAMAM to form gold nanoparticles in the protein cage thermosome

Martin G. Nussbaumer, Christoph Bisig, Nico Bruns^*

^*Corresponding author for this work

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

28 Downloads (Pure)

Abstract

The chaperonin thermosome (THS) is a protein cage that lacks binding sites for metal ions and inorganic nanoparticles. However, when poly(amidoamine) (PAMAM) is encapsulated into THS, gold nanoparticles (AuNP) can be prepared in the THS. The polymer binds HAuCl₄. Subsequent reduction yields nanoparticles with narrow size distribution in the protein-polymer conjugate.

Original language	English
Pages (from-to)	10537-10539
Number of pages	3
Journal	Chemical Communications
Volume	52
Issue number	69
Early online date	27 Jul 2016
DOIs	https://doi.org/10.1039/c6cc04739d
Publication status	Published - 7 Sept 2016

Funding

Financial support by the Marie-Curie Actions of the European Union, the Swiss National Science Foundation, the Holcim Stiftung Wissen and the Swiss Nanoscience Institute is gratefully acknowledged. We thank Vesna Oliveri (ZMB, University of Basel) for TEM expertise.

Keywords

PAMAM
gold nanoparticles
protein cages

Access to Document

10.1039/c6cc04739d

Nussbaumer-etal-CC-2016-Using-the-dendritic-polymer-PAMAM-to-form-goldAccepted author manuscript, 3.58 MB

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abstract = "The chaperonin thermosome (THS) is a protein cage that lacks binding sites for metal ions and inorganic nanoparticles. However, when poly(amidoamine) (PAMAM) is encapsulated into THS, gold nanoparticles (AuNP) can be prepared in the THS. The polymer binds HAuCl4. Subsequent reduction yields nanoparticles with narrow size distribution in the protein-polymer conjugate.",

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AB - The chaperonin thermosome (THS) is a protein cage that lacks binding sites for metal ions and inorganic nanoparticles. However, when poly(amidoamine) (PAMAM) is encapsulated into THS, gold nanoparticles (AuNP) can be prepared in the THS. The polymer binds HAuCl4. Subsequent reduction yields nanoparticles with narrow size distribution in the protein-polymer conjugate.

KW - PAMAM

KW - gold nanoparticles

KW - protein cages

UR - https://www.scopus.com/pages/publications/84983628221

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Using the dendritic polymer PAMAM to form gold nanoparticles in the protein cage thermosome

Abstract

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Keywords

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