Using the dendritic polymer PAMAM to form gold nanoparticles in the protein cage thermosome

Martin G. Nussbaumer, Christoph Bisig, Nico Bruns

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Abstract

The chaperonin thermosome (THS) is a protein cage that lacks binding sites for metal ions and inorganic nanoparticles. However, when poly(amidoamine) (PAMAM) is encapsulated into THS, gold nanoparticles (AuNP) can be prepared in the THS. The polymer binds HAuCl4. Subsequent reduction yields nanoparticles with narrow size distribution in the protein-polymer conjugate.

Original languageEnglish
Pages (from-to)10537-10539
Number of pages3
JournalChemical Communications
Volume52
Issue number69
Early online date27 Jul 2016
DOIs
Publication statusPublished - 7 Sep 2016

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Keywords

  • PAMAM
  • gold nanoparticles
  • protein cages

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