Abstract
INTRODUCTION
- A CFI reactor consist of a inner tube wrapped around a circular frame. This geometry leads to the formation of secondary flow patterns (Dean vortices) known to improve radial mixing.
- Better radial mixing results in a tighter residence time distribution (𝑅𝑅𝑅𝑅𝑅𝑅). Many processes, such as virus inactivation, require a tight 𝑅𝑅𝑅𝑅𝑅𝑅 to avoid unwanted transformations or product damage.
- The tightness of the 𝑅𝑅𝑅𝑅𝑅𝑅 can be evaluated using the relative width (𝑅𝑅𝑤𝑤), the ratio between the minimum and maximum residence times. An 𝑅𝑅𝑤𝑤 value of 1 corresponds to an ideal plug flow reactor.
- A CFI reactor consist of a inner tube wrapped around a circular frame. This geometry leads to the formation of secondary flow patterns (Dean vortices) known to improve radial mixing.
- Better radial mixing results in a tighter residence time distribution (𝑅𝑅𝑅𝑅𝑅𝑅). Many processes, such as virus inactivation, require a tight 𝑅𝑅𝑅𝑅𝑅𝑅 to avoid unwanted transformations or product damage.
- The tightness of the 𝑅𝑅𝑅𝑅𝑅𝑅 can be evaluated using the relative width (𝑅𝑅𝑤𝑤), the ratio between the minimum and maximum residence times. An 𝑅𝑅𝑤𝑤 value of 1 corresponds to an ideal plug flow reactor.
| Original language | English |
|---|---|
| Pages | 11-11 |
| Number of pages | 1 |
| Publication status | Published - 16 May 2022 |
| Event | CMAC Annual Open Day 2022 - Glasgow, United Kingdom Duration: 16 May 2022 → 18 May 2022 |
Conference
| Conference | CMAC Annual Open Day 2022 |
|---|---|
| Country/Territory | United Kingdom |
| City | Glasgow |
| Period | 16/05/22 → 18/05/22 |
Keywords
- Coiled Flow Inverter reactor
- CFI reactor
- machine learning
- flow patterns