Use of slow release starch (SRS) to treat hypoglycaemia in type 1 diabetics

E. Qi, M. Band, R.F. Tester, J.R. Piggott, S. Hurel

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The purpose of this paper is to evaluate if slow release starch (SRS) could be used to control/limit hypoglycaemia in type 1 diabetics. Ten type-1 diabetic volunteers were fitted with continuous glucose monitors for two periods of 3 days when undertaking their normal routine or when consuming 60?g SRS before sleep. The average number of nocturnal hypoglycaemic episodes where no SRS was consumed over 3 days was 2.7?±?2.0 but only 0.7?±?1.1 after SRS consumption before sleep. The duration of these events was equivalent to 318?±?282 and 140?±?337?min, respectively. Average nocturnal blood glucose concentration was 7.9?±?1.4?mmol?l-1 without SRS consumption but increased to 9.7?±?2.7?mmol?l-1 when SRS was consumed. These data were highly significant when subjected to analysis of variance (ANOVA) test on a subject by subject basis. The SRS may be used as a cost effective therapy to avoid hypoglycaemia in patients with type-1 diabetes. This paper reports for the first time the use of a physically modified waxy maize starch (SRS) to prevent/limit the incidence of nocturnal hypoglycaemia in type 1 diabetics.
LanguageEnglish
Pages228-234
Number of pages6
JournalNutrition and Food Science
Volume40
Issue number2
DOIs
Publication statusPublished - 2010

Fingerprint

hypoglycemia
Hypoglycemia
Starch
starch
sleep
Sleep
waxy corn
insulin-dependent diabetes mellitus
corn starch
blood glucose
volunteers
Type 1 Diabetes Mellitus
Hypoglycemic Agents
Zea mays
Blood Glucose
analysis of variance
Volunteers
Analysis of Variance
incidence
therapeutics

Keywords

  • diabetes
  • starches
  • hypoglycaemia

Cite this

Qi, E. ; Band, M. ; Tester, R.F. ; Piggott, J.R. ; Hurel, S. / Use of slow release starch (SRS) to treat hypoglycaemia in type 1 diabetics. In: Nutrition and Food Science. 2010 ; Vol. 40, No. 2. pp. 228-234.
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Use of slow release starch (SRS) to treat hypoglycaemia in type 1 diabetics. / Qi, E.; Band, M.; Tester, R.F.; Piggott, J.R.; Hurel, S.

In: Nutrition and Food Science, Vol. 40, No. 2, 2010, p. 228-234.

Research output: Contribution to journalArticle

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