Understanding the biological safety of silica nanoparticles

Grahame Busby, Siddharth Patwardhan, Andrew Urquhart, Mary Grant

Research output: Contribution to conferenceAbstract

Abstract

The toxicity of a new class of silica nanoparticles synthesised using bioinspired approaches, i.e. neutral pH, room temperature and all-aqueous environments, has been assessed. Traditional Sol-Gel production of silica nanoparticles involves harsh conditions and toxic precursors. The toxicity of bioinspired silica has not been previously reported despite potential applications in drug delivery, biocatalysis and environmental remediation.
LanguageEnglish
Pages1
Publication statusPublished - Sep 2012
EventBritich Toxicology Meeting - Keele, United Kingdom
Duration: 10 Sep 201211 Sep 2012

Conference

ConferenceBritich Toxicology Meeting
CountryUnited Kingdom
CityKeele
Period10/09/1211/09/12

Fingerprint

Silicon Dioxide
Nanoparticles
Biocatalysis
Safety
Poisons
Silica Gel
Polymethyl Methacrylate
Temperature
Pharmaceutical Preparations
Environmental Restoration and Remediation

Keywords

  • drug delivery
  • mesoporous silica nanoparticles
  • cell toxicity

Cite this

Busby, G., Patwardhan, S., Urquhart, A., & Grant, M. (2012). Understanding the biological safety of silica nanoparticles. 1. Abstract from Britich Toxicology Meeting , Keele, United Kingdom.
Busby, Grahame ; Patwardhan, Siddharth ; Urquhart, Andrew ; Grant, Mary. / Understanding the biological safety of silica nanoparticles. Abstract from Britich Toxicology Meeting , Keele, United Kingdom.
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Busby, G, Patwardhan, S, Urquhart, A & Grant, M 2012, 'Understanding the biological safety of silica nanoparticles' Britich Toxicology Meeting , Keele, United Kingdom, 10/09/12 - 11/09/12, pp. 1.

Understanding the biological safety of silica nanoparticles. / Busby, Grahame; Patwardhan, Siddharth; Urquhart, Andrew; Grant, Mary.

2012. 1 Abstract from Britich Toxicology Meeting , Keele, United Kingdom.

Research output: Contribution to conferenceAbstract

TY - CONF

T1 - Understanding the biological safety of silica nanoparticles

AU - Busby, Grahame

AU - Patwardhan, Siddharth

AU - Urquhart, Andrew

AU - Grant, Mary

PY - 2012/9

Y1 - 2012/9

N2 - The toxicity of a new class of silica nanoparticles synthesised using bioinspired approaches, i.e. neutral pH, room temperature and all-aqueous environments, has been assessed. Traditional Sol-Gel production of silica nanoparticles involves harsh conditions and toxic precursors. The toxicity of bioinspired silica has not been previously reported despite potential applications in drug delivery, biocatalysis and environmental remediation.

AB - The toxicity of a new class of silica nanoparticles synthesised using bioinspired approaches, i.e. neutral pH, room temperature and all-aqueous environments, has been assessed. Traditional Sol-Gel production of silica nanoparticles involves harsh conditions and toxic precursors. The toxicity of bioinspired silica has not been previously reported despite potential applications in drug delivery, biocatalysis and environmental remediation.

KW - drug delivery

KW - mesoporous silica nanoparticles

KW - cell toxicity

UR - http://www.thebts.org/ScientificMeetings/MeetingsCalendar/

UR - http://www.thebts.org/Portals/0/Conferences/abstracts/BTS_AM2012/BTS_AM2012P007.pdf

M3 - Abstract

SP - 1

ER -

Busby G, Patwardhan S, Urquhart A, Grant M. Understanding the biological safety of silica nanoparticles. 2012. Abstract from Britich Toxicology Meeting , Keele, United Kingdom.