Understanding drying effects on active pharmaceutical ingredient particle properties

Mariam Siddique; Audrey Laux; Sara Ottoboni; Chris Price; Paul Mulheran

Understanding drying effects on active pharmaceutical ingredient particle properties

Mariam Siddique, Audrey Laux, Sara Ottoboni, Chris Price, Paul Mulheran

Chemical And Process Engineering

Research output: Contribution to conference › Poster

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Abstract

The anticipated impact of the research will be to deliver strategies to mitigate undesired granule formation (lumping) and particle breakage which routinely occur during drying and to develop these into a workflow. The main objective of this work is to quantify the amount of deposited material which can cause lump formation. This has been addressed using glass spheres of different sizes and paracetamol (PCM) solutions of different concentrations.

Original language	English
Pages	73-73
Number of pages	1
Publication status	Published - 16 May 2022
Event	CMAC Annual Open Day 2022 - Glasgow, United Kingdom Duration: 16 May 2022 → 18 May 2022

Conference

Conference	CMAC Annual Open Day 2022
Country/Territory	United Kingdom
City	Glasgow
Period	16/05/22 → 18/05/22

Keywords

granule formulation
particle breakage

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Siddique-etal-CMAC-2022-Understanding-drying-effects-on-active-pharmaceutical-ingredient-particleFinal published version, 2.56 MBLicence: Strath_1

Cite this

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title = "Understanding drying effects on active pharmaceutical ingredient particle properties",

abstract = "The anticipated impact of the research will be to deliver strategies to mitigate undesired granule formation (lumping) and particle breakage which routinely occur during drying and to develop these into a workflow. The main objective of this work is to quantify the amount of deposited material which can cause lump formation. This has been addressed using glass spheres of different sizes and paracetamol (PCM) solutions of different concentrations.",

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author = "Mariam Siddique and Audrey Laux and Sara Ottoboni and Chris Price and Paul Mulheran",

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T1 - Understanding drying effects on active pharmaceutical ingredient particle properties

AU - Siddique, Mariam

AU - Laux, Audrey

AU - Ottoboni, Sara

AU - Price, Chris

AU - Mulheran, Paul

PY - 2022/5/16

Y1 - 2022/5/16

N2 - The anticipated impact of the research will be to deliver strategies to mitigate undesired granule formation (lumping) and particle breakage which routinely occur during drying and to develop these into a workflow. The main objective of this work is to quantify the amount of deposited material which can cause lump formation. This has been addressed using glass spheres of different sizes and paracetamol (PCM) solutions of different concentrations.

AB - The anticipated impact of the research will be to deliver strategies to mitigate undesired granule formation (lumping) and particle breakage which routinely occur during drying and to develop these into a workflow. The main objective of this work is to quantify the amount of deposited material which can cause lump formation. This has been addressed using glass spheres of different sizes and paracetamol (PCM) solutions of different concentrations.

KW - granule formulation

KW - particle breakage

M3 - Poster

SP - 73

EP - 73

T2 - CMAC Annual Open Day 2022

Y2 - 16 May 2022 through 18 May 2022

ER -

Understanding drying effects on active pharmaceutical ingredient particle properties

Abstract

Conference

Keywords

Access to Document

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Cite this