Ultrasonic monitoring of artificial tissue mechanical properties in biorreactor

Guillermo Rus; Nicolas Bochud; Juan Melchor; Laura Peralta; Juan Chiachio; Manuel Chiachio; Antonio Gomez; Juan Antonio Marchal

Ultrasonic monitoring of artificial tissue mechanical properties in biorreactor

Guillermo Rus, Nicolas Bochud, Juan Melchor, Laura Peralta, Juan Chiachio, Manuel Chiachio, Antonio Gomez, Juan Antonio Marchal

Naval Architecture, Ocean And Marine Engineering

Research output: Contribution to conference › Proceeding › peer-review

Abstract

Quantitative control of tissue processes in bioreactors is an open problem in tissue engineering, aimed at creating artificial tissues and organs. To standardize and optimize the process, it is necessary to control most of the parameters that may vary its effectiveness. We propose to monitor the changes that may suffer the matrix during the process using mechanical parameters. To ensure the viability of this protocol, a bioreactor has been designed. The proposed methodology consists of three elements: an (1) experimental setup based on ultrasound-tissue interactions monitored in real-time, a (2) computational model that simulates the ultrasound-tissue interactions, and a (3) model-based inverse problem to reconstruct the evolution of the mechanical parameters

Original language	English
Pages	77-83
Number of pages	7
Publication status	Published - 2014
Event	International Work-Conference on Bioinformatics and Biomedical Engineering - Granada, Spain Duration: 1 Jul 2014 → …

Conference

Conference	International Work-Conference on Bioinformatics and Biomedical Engineering
Abbreviated title	IWBBIO 2014
Country/Territory	Spain
City	Granada
Period	1/07/14 → …

Keywords

ultrasonic monitoring
artificial tissue
mechanical parameters
bioreactor
ultrasound-tissue interactions

Cite this

@conference{3cabac0d0af4434a88b99b0af987518f,

title = "Ultrasonic monitoring of artificial tissue mechanical properties in biorreactor",

abstract = "Quantitative control of tissue processes in bioreactors is an open problem in tissue engineering, aimed at creating artificial tissues and organs. To standardize and optimize the process, it is necessary to control most of the parameters that may vary its effectiveness. We propose to monitor the changes that may suffer the matrix during the process using mechanical parameters. To ensure the viability of this protocol, a bioreactor has been designed. The proposed methodology consists of three elements: an (1) experimental setup based on ultrasound-tissue interactions monitored in real-time, a (2) computational model that simulates the ultrasound-tissue interactions, and a (3) model-based inverse problem to reconstruct the evolution of the mechanical parameters",

keywords = "ultrasonic monitoring, artificial tissue, mechanical parameters, bioreactor, ultrasound-tissue interactions",

author = "Guillermo Rus and Nicolas Bochud and Juan Melchor and Laura Peralta and Juan Chiachio and Manuel Chiachio and Antonio Gomez and {Antonio Marchal}, Juan",

year = "2014",

language = "English",

pages = "77--83",

note = "International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2014 ; Conference date: 01-07-2014",

}

TY - CONF

T1 - Ultrasonic monitoring of artificial tissue mechanical properties in biorreactor

AU - Rus, Guillermo

AU - Bochud, Nicolas

AU - Melchor, Juan

AU - Peralta, Laura

AU - Chiachio, Juan

AU - Chiachio, Manuel

AU - Gomez, Antonio

AU - Antonio Marchal, Juan

PY - 2014

Y1 - 2014

N2 - Quantitative control of tissue processes in bioreactors is an open problem in tissue engineering, aimed at creating artificial tissues and organs. To standardize and optimize the process, it is necessary to control most of the parameters that may vary its effectiveness. We propose to monitor the changes that may suffer the matrix during the process using mechanical parameters. To ensure the viability of this protocol, a bioreactor has been designed. The proposed methodology consists of three elements: an (1) experimental setup based on ultrasound-tissue interactions monitored in real-time, a (2) computational model that simulates the ultrasound-tissue interactions, and a (3) model-based inverse problem to reconstruct the evolution of the mechanical parameters

AB - Quantitative control of tissue processes in bioreactors is an open problem in tissue engineering, aimed at creating artificial tissues and organs. To standardize and optimize the process, it is necessary to control most of the parameters that may vary its effectiveness. We propose to monitor the changes that may suffer the matrix during the process using mechanical parameters. To ensure the viability of this protocol, a bioreactor has been designed. The proposed methodology consists of three elements: an (1) experimental setup based on ultrasound-tissue interactions monitored in real-time, a (2) computational model that simulates the ultrasound-tissue interactions, and a (3) model-based inverse problem to reconstruct the evolution of the mechanical parameters

KW - ultrasonic monitoring

KW - artificial tissue

KW - mechanical parameters

KW - bioreactor

KW - ultrasound-tissue interactions

M3 - Proceeding

SP - 77

EP - 83

T2 - International Work-Conference on Bioinformatics and Biomedical Engineering

Y2 - 1 July 2014

ER -

Ultrasonic monitoring of artificial tissue mechanical properties in biorreactor

Abstract

Conference

Keywords

Fingerprint

Cite this