Trypanocidal active compounds from Scottish Abies nobilis and Pinus sylvestris.

Jamal Elmezughi, Carol Clements, Veronique Seidel, Alexander Gray

Research output: Contribution to journalArticle

Abstract

Three active compounds obtained from the aerial parts of Abies nobilis and Pinus sylvestris isolated by different chromatographic techniques. Their structures were identified by NMR (1H,13C, COSY, HMBC) spectroscopic and mass spectrometric data and established as catechin, dehydroabietic acid and Dihydroconiferyl alcohol. The isolated compounds
were exhibited activity against blood stream form of parasite Trypanosoma brucei brucei
(S 427).
Original languageEnglish
Pages (from-to)56-59
Number of pages4
JournalInternational Research Journal of Pharmacy
Volume4
Issue number2
Publication statusPublished - 2013

Keywords

  • pinaceae
  • Abies nobilis
  • Pinus sylvestris
  • flavanol
  • diterpene
  • cinnamic acid
  • antitrypanocidal activity

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