Trends in the prescribing of antipsychotic medicines in Pakistan: implications for the future

Sidra Mahmood, Shahzad Hussain, Taufeeq ur Rehman, Corrado Barbui, Amanj Baker Kurdi, Brian Godman

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Introduction and objectives: There is a paucity of antipsychotic prescribing and utilization data in Pakistan. This needs addressing especially with issues of availability, affordability, gender differences, and domestic violence, to develop pertinent strategies. The objective of this study was to address these issues by describing current antipsychotic utilization patterns in Pakistan among adult patients attending tertiary care hospitals and private practitioners. Methods: A three staged approach was used including 1/ assessment of total antipsychotic utilization, expenditure and costs per unit between 2010 and 2015, 2/ an in-depth retrospective study of prescribing patterns including co-morbidities among representative hospital patients in Pakistan, and 3/ assessment of the quality of prescribing against WHO targets. Results: Total use of antipsychotics increased 4.3-fold and the cost/unit increased by 13.2% during the study period. Risperidone and olanzapine were the most prescribed antipsychotics with more limited use of other typical and atypical antipsychotics. The number of medicines per encounter was 4.56. Prescription using generic instead of brand names was 21.4%. Seven percent was prescribed more than one antipsychotic concurrently. Conclusion: There has been an appreciable increase in anti-psychotic utilization in recent years in Pakistan especially atypical antipsychotics, with little polypharmacy. Ongoing utilization of typical antipsychotics may be due to comorbidities such as diabetes and cardiovascular disease. Issues of international non-proprietary name prescribing need investigating along with the high number of medicines per encounter and gender inequality.
LanguageEnglish
Pages51-61
Number of pages10
JournalCurrent Medical Research and Opinion
Volume35
Issue number1
Early online date18 Aug 2018
DOIs
Publication statusPublished - 24 Dec 2018

Fingerprint

Pakistan
Antipsychotic Agents
olanzapine
Names
Patient Advocacy
Costs and Cost Analysis
Polypharmacy
Domestic Violence
Risperidone
Tertiary Healthcare
Health Expenditures
Tertiary Care Centers
Prescriptions
Comorbidity
Cardiovascular Diseases
Retrospective Studies
Morbidity

Keywords

  • antipsychotic drugs
  • bipolar disorder
  • drug utilization
  • generics
  • Pakistan
  • schizophrenia

Cite this

Mahmood, Sidra ; Hussain, Shahzad ; ur Rehman, Taufeeq ; Barbui, Corrado ; Kurdi, Amanj Baker ; Godman, Brian. / Trends in the prescribing of antipsychotic medicines in Pakistan : implications for the future. In: Current Medical Research and Opinion. 2018 ; Vol. 35, No. 1. pp. 51-61.
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Trends in the prescribing of antipsychotic medicines in Pakistan : implications for the future. / Mahmood, Sidra; Hussain, Shahzad; ur Rehman, Taufeeq; Barbui, Corrado; Kurdi, Amanj Baker; Godman, Brian.

In: Current Medical Research and Opinion, Vol. 35, No. 1, 24.12.2018, p. 51-61.

Research output: Contribution to journalArticle

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