Abstract
| Original language | English |
|---|---|
| Title of host publication | Methods. |
| Pages | 65-68 |
| Number of pages | 4 |
| Volume | 38 |
| Publication status | Published - 2006 |
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Keywords
- vaccines
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Translation of an experimental oral vaccine formulation into a commercial product. / Carter, Katharine; Ferro, Valerie; Alexander , James ; Mullen, Alexander.
Methods.. Vol. 38 2006. p. 65-68.Research output: Chapter in Book/Report/Conference proceeding › Chapter
TY - CHAP
T1 - Translation of an experimental oral vaccine formulation into a commercial product.
AU - Carter, Katharine
AU - Ferro, Valerie
AU - Alexander , James
AU - Mullen, Alexander
PY - 2006
Y1 - 2006
N2 - An effective experimental vaccine may fail to become a therapeutic reality for a number of scientific, regulatory or commercial reasons. In this review, we share some of our personal experiences as University-based researchers and provide an account of some of the problems that we have encountered during preliminary scale-up and assessment of an oral influenza vaccine formulation. Many of the problems we have faced have been non-scientific and related to identifying project-funding sources, finding suitable contract manufacturing companies that are GMP compliant, and protecting intellectual property generated from the scientific studies. The review is intended as a practical guide that will allow other researchers to adopt effective strategies to permit the translation of an effective experimental formulation to a viable commercial product.
AB - An effective experimental vaccine may fail to become a therapeutic reality for a number of scientific, regulatory or commercial reasons. In this review, we share some of our personal experiences as University-based researchers and provide an account of some of the problems that we have encountered during preliminary scale-up and assessment of an oral influenza vaccine formulation. Many of the problems we have faced have been non-scientific and related to identifying project-funding sources, finding suitable contract manufacturing companies that are GMP compliant, and protecting intellectual property generated from the scientific studies. The review is intended as a practical guide that will allow other researchers to adopt effective strategies to permit the translation of an effective experimental formulation to a viable commercial product.
KW - vaccines
M3 - Chapter
VL - 38
SP - 65
EP - 68
BT - Methods.
ER -