Transamination chemistry of sodium TMP-zincate: synthesis and crystal structure of a chiral amidozincate

D.R. Armstrong, W. Clegg, S.H. Dale, Joaquin Garcia-Alvarez, R.W. Harrington, E. Hevia, G.W. Honeyman, A.R. Kennedy, R.E. Mulvey, C.T. O'Hara

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

In a new type of reactivity for sodium TMP-zincate [(TMEDA) NaZn(Bu-t)(2)(TMP)] (1), transamination reactions with the amines diisopropylamine, DA(H), hexamethyldisilazane, HMDS(H) and chiral (R)-N-benzyl-alpha-methylbenzylamine have produced new sodium amido-di-tert-butyl zincates (all structurally characterised) with concomitant loss of TMP(H).
Original languageEnglish
Pages (from-to)187-189
Number of pages2
JournalChemical Communications (London)
Issue number2
DOIs
Publication statusPublished - 2008

Keywords

  • metal mediated zincation
  • directed ortho metalation
  • magnesium
  • amides
  • base
  • reactivity
  • complexes
  • alkoxides
  • alkyl

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