Trans-metal-trapping: concealed crossover complexes en route to transmetallation?

Marina Uzelac, Robert E. Mulvey

Research output: Contribution to journalLiterature review

8 Citations (Scopus)

Abstract

Defined as the transfer of ligands from one metal to another, transmetallation is a common reaction in organometallic chemistry. Its chemical celebrity stems from its role in important catalytic cycles of cross-coupling reactions such as those of Negishi, Sonogashira, Stille, or Suzuki. This article focuses on trans-metal-trapping (TMT), which could be construed as partially complete transmetallations. On mixing two distinct organometallic compounds, of for example lithium with aluminium or gallium, the two metals meet in a crossover co-complex, but the reaction ceases at that point and full transmetallation is not reached. Though in its infancy, trans-metal-trapping shows promise in transforming failed lithiations into successful lithiations and in stabilising sensitive carbanions through cooperative bimetallic effects making them more amenable to onward reactivity.
LanguageEnglish
Pages7786-7793
Number of pages8
JournalChemistry - A European Journal
Volume24
Issue number31
Early online date30 Apr 2018
DOIs
Publication statusPublished - 4 Jun 2018

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Metals
Organometallic Compounds
Gallium
Organometallics
Aluminum
Lithium
Ligands

Keywords

  • main group elements
  • metallation
  • organometallic chemistry
  • transmetallation
  • trans-metal-trapping

Cite this

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title = "Trans-metal-trapping: concealed crossover complexes en route to transmetallation?",
abstract = "Defined as the transfer of ligands from one metal to another, transmetallation is a common reaction in organometallic chemistry. Its chemical celebrity stems from its role in important catalytic cycles of cross-coupling reactions such as those of Negishi, Sonogashira, Stille, or Suzuki. This article focuses on trans-metal-trapping (TMT), which could be construed as partially complete transmetallations. On mixing two distinct organometallic compounds, of for example lithium with aluminium or gallium, the two metals meet in a crossover co-complex, but the reaction ceases at that point and full transmetallation is not reached. Though in its infancy, trans-metal-trapping shows promise in transforming failed lithiations into successful lithiations and in stabilising sensitive carbanions through cooperative bimetallic effects making them more amenable to onward reactivity.",
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Trans-metal-trapping : concealed crossover complexes en route to transmetallation? / Uzelac, Marina; Mulvey, Robert E.

In: Chemistry - A European Journal, Vol. 24, No. 31, 04.06.2018, p. 7786-7793.

Research output: Contribution to journalLiterature review

TY - JOUR

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T2 - Chemistry - A European Journal

AU - Uzelac, Marina

AU - Mulvey, Robert E.

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N2 - Defined as the transfer of ligands from one metal to another, transmetallation is a common reaction in organometallic chemistry. Its chemical celebrity stems from its role in important catalytic cycles of cross-coupling reactions such as those of Negishi, Sonogashira, Stille, or Suzuki. This article focuses on trans-metal-trapping (TMT), which could be construed as partially complete transmetallations. On mixing two distinct organometallic compounds, of for example lithium with aluminium or gallium, the two metals meet in a crossover co-complex, but the reaction ceases at that point and full transmetallation is not reached. Though in its infancy, trans-metal-trapping shows promise in transforming failed lithiations into successful lithiations and in stabilising sensitive carbanions through cooperative bimetallic effects making them more amenable to onward reactivity.

AB - Defined as the transfer of ligands from one metal to another, transmetallation is a common reaction in organometallic chemistry. Its chemical celebrity stems from its role in important catalytic cycles of cross-coupling reactions such as those of Negishi, Sonogashira, Stille, or Suzuki. This article focuses on trans-metal-trapping (TMT), which could be construed as partially complete transmetallations. On mixing two distinct organometallic compounds, of for example lithium with aluminium or gallium, the two metals meet in a crossover co-complex, but the reaction ceases at that point and full transmetallation is not reached. Though in its infancy, trans-metal-trapping shows promise in transforming failed lithiations into successful lithiations and in stabilising sensitive carbanions through cooperative bimetallic effects making them more amenable to onward reactivity.

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