Tracking the structural changes in a series of cholesterol solvates

Rhona J. Galloway; Syed A. Raza; Robert D. Young; Iain D. H. Oswald

doi:10.1021/cg200971f

Tracking the structural changes in a series of cholesterol solvates

Rhona J. Galloway, Syed A. Raza, Robert D. Young, Iain D. H. Oswald

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

This article describes the isolation of seven new solvates of cholesterol using solvents of varying carbon chain length and overall size from propanol through to phenylethanol. The structural similarities that exist between these novel solid forms and also those cocrystals and solvates already observed are discussed.

Original language	English
Pages (from-to)	231-239
Number of pages	9
Journal	Crystal Growth and Design
Volume	12
Issue number	1
DOIs	https://doi.org/10.1021/cg200971f
Publication status	Published - Jan 2012

Keywords

pseudosymmetry
sphingomyelins
gallstones
crystals
cholesterol solvates

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10.1021/cg200971f

Physical Organic Chemistry: Opportunities In Synthesis, Materials And Pharmaceuticals (Science And Innovation Award)
Murphy, J. (Principal Investigator), Coombs, G. (Co-investigator), Ferguson, A. (Co-investigator) & Florence, A. (Co-investigator)
Scottish Funding Council SFC, EPSRC (Engineering and Physical Sciences Research Council)
1/09/07 → 30/10/12
Project: Research

Cite this

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title = "Tracking the structural changes in a series of cholesterol solvates",

abstract = "This article describes the isolation of seven new solvates of cholesterol using solvents of varying carbon chain length and overall size from propanol through to phenylethanol. The structural similarities that exist between these novel solid forms and also those cocrystals and solvates already observed are discussed.",

keywords = "pseudosymmetry, sphingomyelins, gallstones, crystals, cholesterol solvates",

author = "Galloway, {Rhona J.} and Raza, {Syed A.} and Young, {Robert D.} and Oswald, {Iain D. H.}",

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AU - Young, Robert D.

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AB - This article describes the isolation of seven new solvates of cholesterol using solvents of varying carbon chain length and overall size from propanol through to phenylethanol. The structural similarities that exist between these novel solid forms and also those cocrystals and solvates already observed are discussed.

KW - pseudosymmetry

KW - sphingomyelins

KW - gallstones

KW - crystals

KW - cholesterol solvates

U2 - 10.1021/cg200971f

DO - 10.1021/cg200971f

M3 - Article

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Tracking the structural changes in a series of cholesterol solvates

Abstract

Keywords

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Projects

Physical Organic Chemistry: Opportunities In Synthesis, Materials And Pharmaceuticals (Science And Innovation Award)

Cite this