Toxicity of codeine, codeinone and oxycodone in hep g2 cells: identification of a codeinone-glutathione conjugate by lC/+ECI-MS/MS

M. Jairaj, D.G. Watson, M.H. Grant, G.G. Skellern

Research output: Contribution to conferencePaper

Abstract

Development of new mass spectrometers and implementation of new analytical methods were the central themes of the conference. This paper focused on the toxicity of codeine, codeinone and oxycodone in hep g2 cells: identification of a codeinone-glutathione conjugate by lC/+ECI-MS/MS.
Original languageEnglish
Publication statusPublished - 2002
Event50th Meeting of the American Society for Mass Spectrometry - Orlando, United States
Duration: 2 Jun 20026 Jun 2002

Conference

Conference50th Meeting of the American Society for Mass Spectrometry
CountryUnited States
CityOrlando
Period2/06/026/06/02
Other

Keywords

  • toxicity
  • codeine
  • codeinone
  • oxycodone
  • hep g2 cells
  • pharmacology
  • biomedical sciences

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    Jairaj, M., Watson, D. G., Grant, M. H., & Skellern, G. G. (2002). Toxicity of codeine, codeinone and oxycodone in hep g2 cells: identification of a codeinone-glutathione conjugate by lC/+ECI-MS/MS. Paper presented at 50th Meeting of the American Society for Mass Spectrometry, Orlando, United States.