Towards the total synthesis of Agariblazeispirol C.

Laura C. Paterson, William J. Kerr, Andrew. Sutherland

Research output: Contribution to conferenceOther


Efforts within our lab. have focused towards the synthesis of Agariblazeispirol C, 1, which was recently isolated from the cultured mycelia of Agaricus blazei. Our proposed pathway for gaining access to Agariblazeispirol C centers on the strategic employment of metal-mediated cyclisation chem. Specifically, an . Pauson-Khand reaction (PKR) will be used to construct the C/D ring section of the natural target, and a novel intramol. Heck reaction will establish the key all carbon quaternary center between rings B and C.
Original languageEnglish
Publication statusPublished - 19 Jun 2009
EventWestCHEM Postgraduate Symposium in Organic Chemistry - Glasgow, United Kingdom
Duration: 19 Jun 2009 → …


ConferenceWestCHEM Postgraduate Symposium in Organic Chemistry
Country/TerritoryUnited Kingdom
Period19/06/09 → …


  • Agariblazeispirol C.
  • metal-mediated cyclisation
  • intramol
  • carbon quaternary center


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