Towards the total synthesis of Agariblazeispirol C.

Laura C. Paterson; William J. Kerr; Andrew. Sutherland

Towards the total synthesis of Agariblazeispirol C.

Laura C. Paterson, William J. Kerr, Andrew. Sutherland

Pure And Applied Chemistry

Research output: Contribution to conference › Other

Abstract

Efforts within our lab. have focused towards the synthesis of Agariblazeispirol C, 1, which was recently isolated from the cultured mycelia of Agaricus blazei. Our proposed pathway for gaining access to Agariblazeispirol C centers on the strategic employment of metal-mediated cyclisation chem. Specifically, an . Pauson-Khand reaction (PKR) will be used to construct the C/D ring section of the natural target, and a novel intramol. Heck reaction will establish the key all carbon quaternary center between rings B and C.

Original language	English
Publication status	Published - 19 Jun 2009
Event	WestCHEM Postgraduate Symposium in Organic Chemistry - Glasgow, United Kingdom Duration: 19 Jun 2009 → …

Conference

Conference	WestCHEM Postgraduate Symposium in Organic Chemistry
Country/Territory	United Kingdom
City	Glasgow
Period	19/06/09 → …

Keywords

Agariblazeispirol C.
metal-mediated cyclisation
intramol
carbon quaternary center

Cite this

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title = "Towards the total synthesis of Agariblazeispirol C.",

abstract = "Efforts within our lab. have focused towards the synthesis of Agariblazeispirol C, 1, which was recently isolated from the cultured mycelia of Agaricus blazei. Our proposed pathway for gaining access to Agariblazeispirol C centers on the strategic employment of metal-mediated cyclisation chem. Specifically, an . Pauson-Khand reaction (PKR) will be used to construct the C/D ring section of the natural target, and a novel intramol. Heck reaction will establish the key all carbon quaternary center between rings B and C. ",

keywords = "Agariblazeispirol C. , metal-mediated cyclisation , intramol , carbon quaternary center",

author = "Paterson, {Laura C.} and Kerr, {William J.} and Andrew. Sutherland",

year = "2009",

month = jun,

day = "19",

language = "English",

note = "WestCHEM Postgraduate Symposium in Organic Chemistry ; Conference date: 19-06-2009",

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TY - CONF

T1 - Towards the total synthesis of Agariblazeispirol C.

AU - Paterson, Laura C.

AU - Kerr, William J.

AU - Sutherland, Andrew.

PY - 2009/6/19

Y1 - 2009/6/19

N2 - Efforts within our lab. have focused towards the synthesis of Agariblazeispirol C, 1, which was recently isolated from the cultured mycelia of Agaricus blazei. Our proposed pathway for gaining access to Agariblazeispirol C centers on the strategic employment of metal-mediated cyclisation chem. Specifically, an . Pauson-Khand reaction (PKR) will be used to construct the C/D ring section of the natural target, and a novel intramol. Heck reaction will establish the key all carbon quaternary center between rings B and C.

AB - Efforts within our lab. have focused towards the synthesis of Agariblazeispirol C, 1, which was recently isolated from the cultured mycelia of Agaricus blazei. Our proposed pathway for gaining access to Agariblazeispirol C centers on the strategic employment of metal-mediated cyclisation chem. Specifically, an . Pauson-Khand reaction (PKR) will be used to construct the C/D ring section of the natural target, and a novel intramol. Heck reaction will establish the key all carbon quaternary center between rings B and C.

KW - Agariblazeispirol C.

KW - metal-mediated cyclisation

KW - intramol

KW - carbon quaternary center

UR - http://www.chem.strath.ac.uk/research/seminars/organic/2008-2009

M3 - Other

T2 - WestCHEM Postgraduate Symposium in Organic Chemistry

Y2 - 19 June 2009

ER -

Towards the total synthesis of Agariblazeispirol C.

Abstract

Conference

Keywords

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