Abstract
The tonotopic arrangement of the auditory cortex is well known and gives rise to the possibility of restoring hearing by stimulating spatial regions of the brain surface. This would elicit the neuronal signalling associated with the perception of certain sound frequencies.
Recent work in the mouse cortex has shown that optogenetic cortical stimulation has the capability to overcome limitations with perceived frequency resolution in patients with cochlear implants [1]. Cortical stimulation devices could also benefit patients who are missing the acoustic nerve or have a malformed cochlea and are unable to benefit from cochlear implants.
As part of the HearLight consortium [2], we are developing a cortical implant to explore restoration of hearing through direct optogenetic stimulation of distinct regions of the mouse cortex.
Recent work in the mouse cortex has shown that optogenetic cortical stimulation has the capability to overcome limitations with perceived frequency resolution in patients with cochlear implants [1]. Cortical stimulation devices could also benefit patients who are missing the acoustic nerve or have a malformed cochlea and are unable to benefit from cochlear implants.
As part of the HearLight consortium [2], we are developing a cortical implant to explore restoration of hearing through direct optogenetic stimulation of distinct regions of the mouse cortex.
| Original language | English |
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| Publication status | Published - 13 Jul 2022 |
| Event | EMBC 2022: 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Glasgow, United Kingdom Duration: 11 Jul 2022 → 15 Jul 2022 https://embc.embs.org/2022/ |
Conference
| Conference | EMBC 2022 |
|---|---|
| Abbreviated title | EMBC 2022 |
| Country/Territory | United Kingdom |
| City | Glasgow |
| Period | 11/07/22 → 15/07/22 |
| Internet address |
Keywords
- optogenetic cortical implants
- mouse cortex
- hearing restoration