Tissue surface as the reference arm in Fourier domain optical coherence tomography

Nikola Krstajic, C.T.A. Brown, Kishan Dholakia, Mario Ettore Giardini

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We present a simple method applicable to common-path Fourier domain optical coherence tomography (OCT) in which the tissue surface is used as the reference arm. We propose using aluminium hydroxide powder as a potential tissue surface diffuser to allow wider application of this method. This technique allows one to avoid placing a reference arm reflective element, such as glass plate, on tissue, and intrinsically avoids both coherent and complex conjugate mirror artifacts associated with glass plates. Aluminium hydroxide can be sprayed onto tissue using spray nozzles commonly found in endoscopes. The sensitivity of the tissue reference arm common-path OCT image is 94 dB for a 50-µs charge-coupled device integration time, and 97.5 dB for a 200-µs CCD integration time.
LanguageEnglish
Article number071305
JournalJournal of Biomedical Optics
Volume17
Issue number7
DOIs
Publication statusPublished - Jul 2012

Fingerprint

Optical tomography
tomography
Tissue
Aluminum Hydroxide
Hydrated alumina
Charge coupled devices
hydroxides
charge coupled devices
spray nozzles
Spray nozzles
aluminum
Glass
endoscopes
Endoscopy
glass
diffusers
optical paths
Powders
artifacts
Mirrors

Keywords

  • optical coherence tomography
  • common-path interferometry
  • tissue surface

Cite this

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Tissue surface as the reference arm in Fourier domain optical coherence tomography. / Krstajic, Nikola; Brown, C.T.A.; Dholakia, Kishan; Giardini, Mario Ettore.

In: Journal of Biomedical Optics, Vol. 17, No. 7, 071305, 07.2012.

Research output: Contribution to journalArticle

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