Projects per year
Abstract
Synchronized states are marked by large-amplitude low-frequency oscillations in the cortex. These states can be seen during quiet waking or slow-wave sleep. Within synchronized states, previous studies have noted a plethora of different types of activity, including delta oscillations (0.5-4 Hz) and slow oscillations (<1 Hz) in the neocortex and large- and small- irregular activity in the hippocampus. However, it is not still fully characterized how neural populations contribute to the synchronized state. Here we apply independent component analysis (ICA) to parse which populations are involved in different kinds of neocortical activity, and find two populations that alternate throughout synchronized states. One population broadly affects neocortical deep layers, and is associated with larger amplitude slower neocortical oscillations. The other population exhibits theta-frequency oscillations that are not easily observed in raw field potential recordings. These theta oscillations apparently come from below the neocortex, suggesting hippocampal origin, and are associated with smaller amplitude faster neocortical oscillations. Relative involvement of these two alternating populations may indicate different modes of operation within synchronized states.
Original language | English |
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Article number | 316 |
Number of pages | 16 |
Journal | Frontiers in Neuroscience |
Volume | 13 |
DOIs | |
Publication status | Published - 12 Apr 2019 |
Keywords
- synchronized state
- independent component analysis
- theta oscillation
- non-REM
- slow oscillation
- delta oscillation
- cortical state
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Dive into the research topics of 'Theta oscillations alternate with high amplitude neocortical population within synchronized states'. Together they form a unique fingerprint.Projects
- 3 Finished
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Age-related and cell-type-specific changes in auditory cortical processing
BBSRC (Biotech & Biological Sciences Research Council)
14/09/15 → 13/09/18
Project: Research
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State-dependent and cell-type-specific information processing in auditory cortex
BBSRC (Biotech & Biological Sciences Research Council)
19/08/13 → 18/08/16
Project: Research
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Pathological ensembles in the auditory thalamocortical circuit following acoustic trauma
MRC (Medical Research Council)
1/12/12 → 31/05/14
Project: Research
Datasets
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Data for: "Theta oscillations alternate with high amplitude neocortical population within synchronized states"
Munro Krull, E. (Data Manager), Sakata, S. (Creator) & Toyoizumi, T. (Supervisor), University of Strathclyde, 2 Apr 2019
DOI: 10.15129/1225d3ad-9728-43a9-8091-5259f091f7a7
Dataset