Activities per year
Nitric oxide (NO) is a toxic, free radical gas with diverse biological roles in eukaryotes and bacteria, being involved in signalling, vasodilation, blood clotting and immunity and as an intermediate in microbial denitrification. Several bacterial transcriptional regulators sense this molecule and regulate the expression of genes involved in both NO detoxification and NO damage repair. However, a recently discovered NO sensing repressor, named NsrR, has gained attention because of its suggested role as a global regulator of the bacterial NO stress response. Recent advances in biochemical and transcriptomic studies of NsrR make it timely to review the current evidence for NsrR as a global regulator and to speculate on the recent controversy over its NO sensing mechanism.
|Number of pages||11|
|Journal||Trends in Microbiology|
|Publication status||Published - 16 Apr 2009|
- nitric oxide
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- 1 Key-note speaker and plenary lectures at conferences
Analysis of free radicals, radical modifications and redox signalling
Nicholas Tucker (Invited speaker)18 Apr 2011 → 19 Apr 2011
Activity: Participating in or organising an event types › Key-note speaker and plenary lectures at conferences