The use of pharmacokinetic and pharmacodynamic end points to determine the dose of AQ4N, a novel hypoxic cell cytotoxin, given with fractionated radiotherapy in a phase I study

W. P. Steward, M. Middleton, A. Benghiat, P. M. Loadman, C. Hayward, S. Waller, S. Ford, G. Halbert, L. H. Patterson, D. Talbot

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Pharmacology, Toxicology and Pharmaceutical Science