The toxicity of troglitazone, roziglitazone and vitamin e in human hep g2 hepatoma cells

A.J. Ball; J.N.A. Tettey; M.H. Grant

doi:10.1016/j.tox.2003.09.003

The toxicity of troglitazone, roziglitazone and vitamin e in human hep g2 hepatoma cells

A.J. Ball, J.N.A. Tettey, M.H. Grant

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Conference Contribution › peer-review

Abstract

Troglitazone (TGZ), a member of the thiazolidinedione class of drugs used to treat type-II diabetes, has been associated with hepatotoxicity (Biswas et al., 2001). TGZ differs structurally from the newer non-hepatotoxic glitazone, rosiglitazone (RGZ), in that it contains the chromanol moiety of Vitamin E (Vit E). This study compares
the toxicity of TGZ, RGZ and Vit E in human HepG2 cells

Original language	English
Pages (from-to)	250-251
Number of pages	2
Journal	Toxicology
Volume	194
Issue number	3
DOIs	https://doi.org/10.1016/j.tox.2003.09.003
Publication status	Published - 2004

Keywords

troglitazone
roziglitazone
toxiciology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tox.2003.09.003

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title = "The toxicity of troglitazone, roziglitazone and vitamin e in human hep g2 hepatoma cells",

abstract = "Troglitazone (TGZ), a member of the thiazolidinedione class of drugs used to treat type-II diabetes, has been associated with hepatotoxicity (Biswas et al., 2001). TGZ differs structurally from the newer non-hepatotoxic glitazone, rosiglitazone (RGZ), in that it contains the chromanol moiety of Vitamin E (Vit E). This study comparesthe toxicity of TGZ, RGZ and Vit E in human HepG2 cells",

keywords = "troglitazone, roziglitazone, toxiciology",

author = "A.J. Ball and J.N.A. Tettey and M.H. Grant",

note = "Abstracts of the British Toxicology Society Annual Congress 2003.",

year = "2004",

doi = "10.1016/j.tox.2003.09.003",

language = "English",

volume = "194",

pages = "250--251",

journal = "Toxicology",

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TY - JOUR

T1 - The toxicity of troglitazone, roziglitazone and vitamin e in human hep g2 hepatoma cells

AU - Ball, A.J.

AU - Tettey, J.N.A.

AU - Grant, M.H.

N1 - Abstracts of the British Toxicology Society Annual Congress 2003.

PY - 2004

Y1 - 2004

N2 - Troglitazone (TGZ), a member of the thiazolidinedione class of drugs used to treat type-II diabetes, has been associated with hepatotoxicity (Biswas et al., 2001). TGZ differs structurally from the newer non-hepatotoxic glitazone, rosiglitazone (RGZ), in that it contains the chromanol moiety of Vitamin E (Vit E). This study comparesthe toxicity of TGZ, RGZ and Vit E in human HepG2 cells

AB - Troglitazone (TGZ), a member of the thiazolidinedione class of drugs used to treat type-II diabetes, has been associated with hepatotoxicity (Biswas et al., 2001). TGZ differs structurally from the newer non-hepatotoxic glitazone, rosiglitazone (RGZ), in that it contains the chromanol moiety of Vitamin E (Vit E). This study comparesthe toxicity of TGZ, RGZ and Vit E in human HepG2 cells

KW - troglitazone

KW - roziglitazone

KW - toxiciology

U2 - 10.1016/j.tox.2003.09.003

DO - 10.1016/j.tox.2003.09.003

M3 - Conference Contribution

SN - 0300-483X

VL - 194

SP - 250

EP - 251

JO - Toxicology

JF - Toxicology

IS - 3

ER -

The toxicity of troglitazone, roziglitazone and vitamin e in human hep g2 hepatoma cells

Abstract

Keywords

UN SDGs

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