The Synthesis of Cyclic Ether-Containing Natural and Non-natural Products by Metathesis Reactions

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter describes recent advances (2005–2015) in the use of metathesis reactions to construct the cyclic ether portions in the total synthesis of natural products. Advances in the synthesis of a range of marine polyether natural products are presented, and various strategic approaches to the bridged pyranmacrocycles neopeltolide and kendomycin are discussed. Finally, the synthesis of a range of biologically active, cyclic ether-based non-natural products is described.
Original languageEnglish
Title of host publicationTopics in Heterocyclic Chemistry
EditorsJ. Prunet
Place of PublicationCham
PublisherSpringer
Chapter2
Pages33-56
Number of pages24
ISBN (Print)9783319399393, 9783319399416
DOIs
Publication statusPublished - 3 Feb 2016

Keywords

  • bioactive compounds
  • cyclisation
  • ether
  • metathesis reactions
  • natural products

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