The role of lyophilisation in the enhancement of glibenclamide release from hard gelatin capsules

H. Mansour; F.J. McInnes; A.J. Florence; A. Mullen

doi:10.1211/002235709789036991

The role of lyophilisation in the enhancement of glibenclamide release from hard gelatin capsules

H. Mansour, F.J. McInnes, A.J. Florence, A. Mullen

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Conference Contribution › peer-review

Abstract

The aim of this study was to enhance the release rate of the hypoglycaemic agent glibenclamide from hard gelatin capsules through co-lyophilisation with sodium lauryl sulphate (SLS) and perform physical characterisation of the lyophilised product.

Original language	English
Pages (from-to)	A38-A39
Journal	Journal of Pharmacy and Pharmacology
Volume	61
Issue number	S1
DOIs	https://doi.org/10.1211/002235709789036991
Publication status	Published - 2009

Keywords

drugs
bioavailability
release rate
glibenclamide
colyophilisation

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10.1211/002235709789036991

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title = "The role of lyophilisation in the enhancement of glibenclamide release from hard gelatin capsules",

abstract = "The aim of this study was to enhance the release rate of the hypoglycaemic agent glibenclamide from hard gelatin capsules through co-lyophilisation with sodium lauryl sulphate (SLS) and perform physical characterisation of the lyophilised product.",

keywords = "drugs, bioavailability, release rate, glibenclamide, colyophilisation",

author = "H. Mansour and F.J. McInnes and A.J. Florence and A. Mullen",

year = "2009",

doi = "10.1211/002235709789036991",

language = "English",

volume = "61",

pages = "A38--A39",

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AU - Mansour, H.

AU - McInnes, F.J.

AU - Florence, A.J.

AU - Mullen, A.

PY - 2009

Y1 - 2009

N2 - The aim of this study was to enhance the release rate of the hypoglycaemic agent glibenclamide from hard gelatin capsules through co-lyophilisation with sodium lauryl sulphate (SLS) and perform physical characterisation of the lyophilised product.

AB - The aim of this study was to enhance the release rate of the hypoglycaemic agent glibenclamide from hard gelatin capsules through co-lyophilisation with sodium lauryl sulphate (SLS) and perform physical characterisation of the lyophilised product.

KW - drugs

KW - bioavailability

KW - release rate

KW - glibenclamide

KW - colyophilisation

U2 - 10.1211/002235709789036991

DO - 10.1211/002235709789036991

M3 - Conference Contribution

SN - 0022-3573

VL - 61

SP - A38-A39

JO - Journal of Pharmacy and Pharmacology

JF - Journal of Pharmacy and Pharmacology

IS - S1

ER -

The role of lyophilisation in the enhancement of glibenclamide release from hard gelatin capsules

Abstract

Keywords

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