Abstract
| Language | English |
|---|---|
| Title of host publication | Advances in manufacturing technology XXXII |
| Subtitle of host publication | proceedings of the 16th International Conference on Manufacturing Research |
| Editors | Peter Thorvald, Keith Case |
| Place of Publication | Netherlands |
| Pages | 27-32 |
| Number of pages | 6 |
| DOIs | |
| Publication status | Published - 11 Sep 2018 |
| Event | International Conference on Manufacturing Research - Skövde, Sweden Duration: 11 Sep 2018 → 13 Sep 2018 |
Conference
| Conference | International Conference on Manufacturing Research |
|---|---|
| Abbreviated title | ICMR '18 |
| Country | Sweden |
| City | Skövde |
| Period | 11/09/18 → 13/09/18 |
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Keywords
- continuous manufacturing
- digitisation
- in-line imaging
Cite this
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The role of in-line image analysis in the transition to continuous manufacturing in the pharmaceutical industry. / Cardona, Javier; Ferreira, Carla; Svoboda, Vaclav; Ahmed, Bilal; McGinty, John; Agimelen, Okpeafoh S.; Hamilton, Andrew; Cleary, Alison; Atkinson, Robert; Michie, Craig; Marshall, Stephen; Florence, Alastair J.; Chen, Yi-Chieh; Sefcik, Jan; Andonovic, Ivan; Tachtatzis, Christos.
Advances in manufacturing technology XXXII: proceedings of the 16th International Conference on Manufacturing Research. ed. / Peter Thorvald; Keith Case. Netherlands, 2018. p. 27-32.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution book
TY - GEN
T1 - The role of in-line image analysis in the transition to continuous manufacturing in the pharmaceutical industry
AU - Cardona, Javier
AU - Ferreira, Carla
AU - Svoboda, Vaclav
AU - Ahmed, Bilal
AU - McGinty, John
AU - Agimelen, Okpeafoh S.
AU - Hamilton, Andrew
AU - Cleary, Alison
AU - Atkinson, Robert
AU - Michie, Craig
AU - Marshall, Stephen
AU - Florence, Alastair J.
AU - Chen, Yi-Chieh
AU - Sefcik, Jan
AU - Andonovic, Ivan
AU - Tachtatzis, Christos
N1 - Cardona, J., Ferreira, C., Svoboda, V., Ahmed, B., McGinty, J., Agimelen, O. S., ... Tachtatzis, C. (2018). The role of in-line image analysis in the transition to continuous manufacturing in the pharmaceutical industry. In P. Thorvald, & K. Case (Eds.), Advances in manufacturing technology XXXII: proceedings of the 16th International Conference on Manufacturing Research (pp. 27-32). Netherlands: IOS Press. https://doi.org/10.3233/978-1-61499-902-7-27, with permission from IOS Press
PY - 2018/9/11
Y1 - 2018/9/11
N2 - In recent years, the pharmaceutical industry is seeing a movement towards the implementation of more efficient continuous manufacturing. This shift requires the development of in-line process analytical technologies to monitor and control the process at any given time. However, extracting reliable information from these sensors is a challenge. Among the available technologies, in-line image analysis is quickly gaining importance. This work presents an image analysis framework developed to address one of the main challenges of in-line image analysis: the presence of out-of-focus particles. Through two relevant examples such as the characterisation of a system of microparticles of mixed shapes and the monitoring of a common operation in the pharmaceutical industry such as the wet milling process, the benefits of incorporating this technique are assessed. The realtime analysis of imaging data in combination with other simultaneously-acquired quantitative data streams enables the user to make informed decisions and implement enhanced control strategies.
AB - In recent years, the pharmaceutical industry is seeing a movement towards the implementation of more efficient continuous manufacturing. This shift requires the development of in-line process analytical technologies to monitor and control the process at any given time. However, extracting reliable information from these sensors is a challenge. Among the available technologies, in-line image analysis is quickly gaining importance. This work presents an image analysis framework developed to address one of the main challenges of in-line image analysis: the presence of out-of-focus particles. Through two relevant examples such as the characterisation of a system of microparticles of mixed shapes and the monitoring of a common operation in the pharmaceutical industry such as the wet milling process, the benefits of incorporating this technique are assessed. The realtime analysis of imaging data in combination with other simultaneously-acquired quantitative data streams enables the user to make informed decisions and implement enhanced control strategies.
KW - continuous manufacturing
KW - digitisation
KW - in-line imaging
UR - http://www.icmr.org.uk/
UR - http://www.iospress.nl
U2 - 10.3233/978-1-61499-902-7-27
DO - 10.3233/978-1-61499-902-7-27
M3 - Conference contribution book
SN - 978-1-61499-901-0
SP - 27
EP - 32
BT - Advances in manufacturing technology XXXII
A2 - Thorvald, Peter
A2 - Case, Keith
CY - Netherlands
ER -