The prevalence, distribution and severity of detectable pathological lesions in badgers naturally infected with Mycobacterium bovis

H.E. Jenkins; W.I. Morrison; D.R. Cox; C.A. Donnelly; W.T. Johnston; F.J. Bourne; R. Clifton-Hadley; G. Gettinby; J.P. McInerney; G.H. Watkins; R. Woodroffe; Department of Environment, Food and Rural Affairs (Defra) (Funder)

doi:10.1017/S0950268807009909

The prevalence, distribution and severity of detectable pathological lesions in badgers naturally infected with Mycobacterium bovis

H.E. Jenkins, W.I. Morrison, D.R. Cox, C.A. Donnelly, W.T. Johnston, F.J. Bourne, R. Clifton-Hadley, G. Gettinby, J.P. McInerney, G.H. Watkins, R. Woodroffe, Department of Environment, Food and Rural Affairs (Defra) (Funder)

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Abstract

The Randomized Badger Culling Trial (RBCT) began in 1998 to determine the impact of badger culling in controlling bovine tuberculosis in cattle. A total of 1166 badgers (14% of total)proactively culled during the RBCT were found to be tuberculous, offering a unique opportunity to study the pathology caused by Mycobacterium bovis in a large sample of badgers. Of these, 39% of adults (y6% of all adults culled) had visible lesions (detectable at necropsy) of bovine tuberculosis ; cubs had a lower prevalence of infection (9%) but a higher percentage of tuberculous cubs (55.5%) had visible lesions. Only ~1% of adult badgers had extensive, severe pathology. Tuberculous badgers with recorded bite wounds (~5%) had a higher prevalence of visible lesions and a different distribution of lesions, suggesting transmission via bite wounds. However, the predominance of lesions in the respiratory tract indicates that most transmission occurs by the respiratory route.

Original language	English
Pages (from-to)	1350-1361
Number of pages	12
Journal	Infection and Epidemiology
Volume	136
Issue number	10
DOIs	https://doi.org/10.1017/S0950268807009909
Publication status	Published - Oct 2008

Keywords

badgers
Mycobacterium bovis
lesions
bovine tuberculosis
randomized badger culling trial

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1017/S0950268807009909

6._helens_pathology_epid_and_infect_paper_finalversion_dec_2007(a).pdfAccepted author manuscript, 124 KB

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Jenkins, H. E., Morrison, W. I., Cox, D. R., Donnelly, C. A., Johnston, W. T., Bourne, F. J., Clifton-Hadley, R., Gettinby, G., McInerney, J. P., Watkins, G. H., Woodroffe, R., & Department of Environment, Food and Rural Affairs (Defra) (Funder) (2008). The prevalence, distribution and severity of detectable pathological lesions in badgers naturally infected with Mycobacterium bovis. Infection and Epidemiology, 136(10), 1350-1361. https://doi.org/10.1017/S0950268807009909

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title = "The prevalence, distribution and severity of detectable pathological lesions in badgers naturally infected with Mycobacterium bovis",

abstract = "The Randomized Badger Culling Trial (RBCT) began in 1998 to determine the impact of badger culling in controlling bovine tuberculosis in cattle. A total of 1166 badgers (14% of total)proactively culled during the RBCT were found to be tuberculous, offering a unique opportunity to study the pathology caused by Mycobacterium bovis in a large sample of badgers. Of these, 39% of adults (y6% of all adults culled) had visible lesions (detectable at necropsy) of bovine tuberculosis ; cubs had a lower prevalence of infection (9%) but a higher percentage of tuberculous cubs (55.5%) had visible lesions. Only ~1% of adult badgers had extensive, severe pathology. Tuberculous badgers with recorded bite wounds (~5%) had a higher prevalence of visible lesions and a different distribution of lesions, suggesting transmission via bite wounds. However, the predominance of lesions in the respiratory tract indicates that most transmission occurs by the respiratory route.",

keywords = "badgers, Mycobacterium bovis, lesions, bovine tuberculosis, randomized badger culling trial",

author = "H.E. Jenkins and W.I. Morrison and D.R. Cox and C.A. Donnelly and W.T. Johnston and F.J. Bourne and R. Clifton-Hadley and G. Gettinby and J.P. McInerney and G.H. Watkins and R. Woodroffe and {Department of Environment, Food and Rural Affairs (Defra) (Funder)}",

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doi = "10.1017/S0950268807009909",

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Jenkins, HE, Morrison, WI, Cox, DR, Donnelly, CA, Johnston, WT, Bourne, FJ, Clifton-Hadley, R, Gettinby, G, McInerney, JP, Watkins, GH, Woodroffe, R & Department of Environment, Food and Rural Affairs (Defra) (Funder) 2008, 'The prevalence, distribution and severity of detectable pathological lesions in badgers naturally infected with Mycobacterium bovis', Infection and Epidemiology, vol. 136, no. 10, pp. 1350-1361. https://doi.org/10.1017/S0950268807009909

TY - JOUR

T1 - The prevalence, distribution and severity of detectable pathological lesions in badgers naturally infected with Mycobacterium bovis

AU - Jenkins, H.E.

AU - Morrison, W.I.

AU - Cox, D.R.

AU - Donnelly, C.A.

AU - Johnston, W.T.

AU - Bourne, F.J.

AU - Clifton-Hadley, R.

AU - Gettinby, G.

AU - McInerney, J.P.

AU - Watkins, G.H.

AU - Woodroffe, R.

AU - Department of Environment, Food and Rural Affairs (Defra) (Funder)

PY - 2008/10

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N2 - The Randomized Badger Culling Trial (RBCT) began in 1998 to determine the impact of badger culling in controlling bovine tuberculosis in cattle. A total of 1166 badgers (14% of total)proactively culled during the RBCT were found to be tuberculous, offering a unique opportunity to study the pathology caused by Mycobacterium bovis in a large sample of badgers. Of these, 39% of adults (y6% of all adults culled) had visible lesions (detectable at necropsy) of bovine tuberculosis ; cubs had a lower prevalence of infection (9%) but a higher percentage of tuberculous cubs (55.5%) had visible lesions. Only ~1% of adult badgers had extensive, severe pathology. Tuberculous badgers with recorded bite wounds (~5%) had a higher prevalence of visible lesions and a different distribution of lesions, suggesting transmission via bite wounds. However, the predominance of lesions in the respiratory tract indicates that most transmission occurs by the respiratory route.

AB - The Randomized Badger Culling Trial (RBCT) began in 1998 to determine the impact of badger culling in controlling bovine tuberculosis in cattle. A total of 1166 badgers (14% of total)proactively culled during the RBCT were found to be tuberculous, offering a unique opportunity to study the pathology caused by Mycobacterium bovis in a large sample of badgers. Of these, 39% of adults (y6% of all adults culled) had visible lesions (detectable at necropsy) of bovine tuberculosis ; cubs had a lower prevalence of infection (9%) but a higher percentage of tuberculous cubs (55.5%) had visible lesions. Only ~1% of adult badgers had extensive, severe pathology. Tuberculous badgers with recorded bite wounds (~5%) had a higher prevalence of visible lesions and a different distribution of lesions, suggesting transmission via bite wounds. However, the predominance of lesions in the respiratory tract indicates that most transmission occurs by the respiratory route.

KW - badgers

KW - Mycobacterium bovis

KW - lesions

KW - bovine tuberculosis

KW - randomized badger culling trial

U2 - 10.1017/S0950268807009909

DO - 10.1017/S0950268807009909

M3 - Article

SN - 0950-2688

VL - 136

SP - 1350

EP - 1361

JO - Infection and Epidemiology

JF - Infection and Epidemiology

IS - 10

ER -

The prevalence, distribution and severity of detectable pathological lesions in badgers naturally infected with Mycobacterium bovis

Abstract

Keywords

UN SDGs

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