The pedunculopontine tegmental nucleus and responding for sucrose reward

James A. Ainge, Glenda L. Keating, Mary P. Latimer, Philip Winn

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Pedunculopontine tegmental nucleus (PPTg) lesions in rodents lead to increased sucrose consumption, but the psychological deficit behind this remains uncertain. To understand better the relationship between consumption of, and motivation for, sucrose, the authors trained rats to traverse a runway for 20% or 4% sucrose solution; after 7 days, concentrations were reversed. Control rats consumed more 20% than 4% sucrose solution and promptly altered run times in response to concentration change. PPTg-lesioned rats consumed normal quantities of 4% but more 20% sucrose solution than controls and took longer to alter their runway time following the concentration change. These data suggest that lesions of the PPTg do not alter motivation per se and might be better understood as inducing a response selection deficit.

LanguageEnglish
Pages563-570
Number of pages8
JournalBehavioral Neuroscience
Volume120
Issue number3
DOIs
Publication statusPublished - 1 Jun 2006

Fingerprint

Pedunculopontine Tegmental Nucleus
Reward
Sucrose
Motivation
Rodentia
Psychology

Keywords

  • mesopontine tegmentum
  • motivation
  • rat
  • reinforcement
  • runway
  • animal experiment
  • controlled study
  • mental concentration
  • reward

Cite this

Ainge, James A. ; Keating, Glenda L. ; Latimer, Mary P. ; Winn, Philip. / The pedunculopontine tegmental nucleus and responding for sucrose reward. In: Behavioral Neuroscience. 2006 ; Vol. 120, No. 3. pp. 563-570.
@article{8b0c2440b5594703b13a42e6b2ddb55f,
title = "The pedunculopontine tegmental nucleus and responding for sucrose reward",
abstract = "Pedunculopontine tegmental nucleus (PPTg) lesions in rodents lead to increased sucrose consumption, but the psychological deficit behind this remains uncertain. To understand better the relationship between consumption of, and motivation for, sucrose, the authors trained rats to traverse a runway for 20{\%} or 4{\%} sucrose solution; after 7 days, concentrations were reversed. Control rats consumed more 20{\%} than 4{\%} sucrose solution and promptly altered run times in response to concentration change. PPTg-lesioned rats consumed normal quantities of 4{\%} but more 20{\%} sucrose solution than controls and took longer to alter their runway time following the concentration change. These data suggest that lesions of the PPTg do not alter motivation per se and might be better understood as inducing a response selection deficit.",
keywords = "mesopontine tegmentum, motivation, rat, reinforcement, runway, animal experiment, controlled study, mental concentration, reward",
author = "Ainge, {James A.} and Keating, {Glenda L.} and Latimer, {Mary P.} and Philip Winn",
year = "2006",
month = "6",
day = "1",
doi = "10.1037/0735-7044.120.3.563",
language = "English",
volume = "120",
pages = "563--570",
journal = "Behavioral Neuroscience",
issn = "0735-7044",
number = "3",

}

The pedunculopontine tegmental nucleus and responding for sucrose reward. / Ainge, James A.; Keating, Glenda L.; Latimer, Mary P.; Winn, Philip.

In: Behavioral Neuroscience, Vol. 120, No. 3, 01.06.2006, p. 563-570.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The pedunculopontine tegmental nucleus and responding for sucrose reward

AU - Ainge, James A.

AU - Keating, Glenda L.

AU - Latimer, Mary P.

AU - Winn, Philip

PY - 2006/6/1

Y1 - 2006/6/1

N2 - Pedunculopontine tegmental nucleus (PPTg) lesions in rodents lead to increased sucrose consumption, but the psychological deficit behind this remains uncertain. To understand better the relationship between consumption of, and motivation for, sucrose, the authors trained rats to traverse a runway for 20% or 4% sucrose solution; after 7 days, concentrations were reversed. Control rats consumed more 20% than 4% sucrose solution and promptly altered run times in response to concentration change. PPTg-lesioned rats consumed normal quantities of 4% but more 20% sucrose solution than controls and took longer to alter their runway time following the concentration change. These data suggest that lesions of the PPTg do not alter motivation per se and might be better understood as inducing a response selection deficit.

AB - Pedunculopontine tegmental nucleus (PPTg) lesions in rodents lead to increased sucrose consumption, but the psychological deficit behind this remains uncertain. To understand better the relationship between consumption of, and motivation for, sucrose, the authors trained rats to traverse a runway for 20% or 4% sucrose solution; after 7 days, concentrations were reversed. Control rats consumed more 20% than 4% sucrose solution and promptly altered run times in response to concentration change. PPTg-lesioned rats consumed normal quantities of 4% but more 20% sucrose solution than controls and took longer to alter their runway time following the concentration change. These data suggest that lesions of the PPTg do not alter motivation per se and might be better understood as inducing a response selection deficit.

KW - mesopontine tegmentum

KW - motivation

KW - rat

KW - reinforcement

KW - runway

KW - animal experiment

KW - controlled study

KW - mental concentration

KW - reward

UR - http://www.scopus.com/inward/record.url?scp=33745905972&partnerID=8YFLogxK

U2 - 10.1037/0735-7044.120.3.563

DO - 10.1037/0735-7044.120.3.563

M3 - Article

VL - 120

SP - 563

EP - 570

JO - Behavioral Neuroscience

T2 - Behavioral Neuroscience

JF - Behavioral Neuroscience

SN - 0735-7044

IS - 3

ER -