The Nitrile Imine 1,3-Dipole: Properties, Reactivity and Applications

Craig Jamieson, Keith Livingstone

Research output: Book/ReportBook

29 Citations (Scopus)


This book provides a comprehensive overview of the nitrilimine 1,3-dipole, from its initial discovery in 1959 to the most recent publications. Covering topics such as the core properties of the dipole and the various methods of synthesis available, it particularly highlights the diverse reactivity profile of the nitrilimine and its numerous applications in bioorthogonal and materials chemistry. The book is of interest to academic and industrial researchers working in this area and to those new to the field.
Original languageEnglish
Place of PublicationCham, Switzerland
PublisherSpringer Nature
Number of pages166
ISBN (Print)9783030434809, 9783030434816
Publication statusPublished - 26 Mar 2020


  • 1,3-dipolar cycloaddition
  • 1,3-dipoles
  • 2,5-tetrazoles
  • bioorthogonal chemistry
  • nitrile imines
  • nitrilium betaine
  • photolysis


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