The motor cortex drives the muscles during walking in human subjects

Tue Petersen, M Willerslev-Olsen, Bernard A Conway, J.B. Nielsen

Research output: Contribution to journalArticle

136 Citations (Scopus)

Abstract

It is often assumed that automatic movements such as walking require little conscious attention and it has therefore been argued that these movements require little cortical control.  In humans, however, the gait function is often heavily impaired or completely lost following cortical lesions such as stroke.  In this study we investigated synchrony between cortical signals recorded with electroencephalography (EEG) and electromyographic signals (EMG activity) recorded from the tibialis anterior muscle (TA) during walking.  We found evidence of synchrony in the frequency domain (coherence) between the primary motor cortex and the TA muscle indicating a cortical involvement in human gait function.  This finding underpins the importance of restoration of the activity and connectivity between the motor cortex and the spinal cord in the recovery of gait function in patients with damage of the central nervous system.
LanguageEnglish
Pages2443-2452
Number of pages10
JournalJournal of Physiology
Volume590
Issue number10
Early online date5 Mar 2012
DOIs
Publication statusPublished - 15 May 2012

Fingerprint

Motor Cortex
Gait
Walking
Muscles
Recovery of Function
Electroencephalography
Spinal Cord
Central Nervous System
Stroke

Keywords

  • walking
  • treadmill walking
  • walking muscles
  • corticospinal tract

Cite this

Petersen, Tue ; Willerslev-Olsen, M ; Conway, Bernard A ; Nielsen, J.B. / The motor cortex drives the muscles during walking in human subjects. In: Journal of Physiology. 2012 ; Vol. 590, No. 10. pp. 2443-2452.
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The motor cortex drives the muscles during walking in human subjects. / Petersen, Tue; Willerslev-Olsen, M; Conway, Bernard A; Nielsen, J.B.

In: Journal of Physiology, Vol. 590, No. 10, 15.05.2012, p. 2443-2452.

Research output: Contribution to journalArticle

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