The mechanical strength of collagen gels containing glycosaminoglycans and populated with fibroblasts

Research output: Contribution to conferencePaper

2 Citations (Scopus)

Abstract

Collagen based scaffolds are widely used for tissue engineering strategies; many are designed to biodegrade gradually and become populated with host cells. The effect of infiltration by host cells on the mechanical properties of the scaffolds is unclear. We have used fibroblast populated collagen lattices to study the effects of the presence of 3T3 mouse fibroblasts on the mechanical properties of collagen gels containing glycosaminoglycans (GAGs) crosslinked with the carbodiimide, 1,1-carbonyldiimidazole (CDI), and the polyamine, putrescine (Put).
Original languageEnglish
Publication statusPublished - 2005
EventTissue and Cell Engineering Society Meeting - London, England
Duration: 20 May 200522 May 2005

Conference

ConferenceTissue and Cell Engineering Society Meeting
CityLondon, England
Period20/05/0522/05/05

Keywords

  • mechanical engineering
  • collagen gels
  • glycosaminoglycans
  • fibroblasts
  • crosslinked collagen
  • fibroblast populated collagen gels
  • collagen/glycosaminoglycan gels

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  • Research Output

    • 2 Citations
    • 1 Article
  • 19 Citations (Scopus)

    Cite this

    Saddiq, Z. A., Barbenel, J. C., & Grant, M. H. (2005). The mechanical strength of collagen gels containing glycosaminoglycans and populated with fibroblasts. Paper presented at Tissue and Cell Engineering Society Meeting, London, England, .