The internal mechanics of the intervertebral disc under cyclic loading

P.E. Riches, N. Dhillon, J. Lotz, A.W. Woods, D.S. McNally

    Research output: Contribution to journalArticle

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    Abstract

    The mechanics of the intervertebral disc (IVD) under cyclic loading are investigated via a one-dimensional poroelastic model and experiment. The poroelastic model, based on that of Biot (J. Appl. Phys. 12 (1941) 155; J. Appl. Mech. 23 (1956) 91), includes a power-law relation between porosity and permeability, and a linear relation between the osmotic potential and solidity. The model was fitted to experimental data of the unconfined IVD undergoing 5 cyclic loads of 20 min compression by an applied stress of 1 MPa, followed by 40 min expansion. To obtain a good agreement between experiment and theory, the initial elastic deformation of the IVD, possibly associated with the bulging of the IVD into the vertebral bodies or laterally, was removed from the experimental data. Many combinations of the permeability-porosity relationship with the initial osmotic potential (πi) were investigated, and the best-fit parameters for the aggregate modulus (HA) and initial permeability (ki) were determined. The values of HA and ki were compared to literature values, and agreed well especially in the context of the adopted high-stress testing regime, and the strain related permeability in the model.
    LanguageEnglish
    Pages1263-1271
    Number of pages8
    JournalJournal of Biomechanics
    Volume35
    Issue number9
    DOIs
    Publication statusPublished - 2002

    Fingerprint

    Intervertebral Disc
    Mechanics
    Permeability
    Porosity
    Cyclic loads
    Elastic deformation
    Experiments
    Testing

    Keywords

    • intervertebral disc
    • poroelastic
    • pharmacology
    • biomedical sciences
    • physiology

    Cite this

    Riches, P.E. ; Dhillon, N. ; Lotz, J. ; Woods, A.W. ; McNally, D.S. / The internal mechanics of the intervertebral disc under cyclic loading. In: Journal of Biomechanics. 2002 ; Vol. 35, No. 9. pp. 1263-1271.
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    The internal mechanics of the intervertebral disc under cyclic loading. / Riches, P.E.; Dhillon, N.; Lotz, J.; Woods, A.W.; McNally, D.S.

    In: Journal of Biomechanics, Vol. 35, No. 9, 2002, p. 1263-1271.

    Research output: Contribution to journalArticle

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    AU - Lotz, J.

    AU - Woods, A.W.

    AU - McNally, D.S.

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