The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts

A. Ganguli, A.W. Lloyd, S.T. Meikle, M.H. Grant

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    Coating of the hydroxyapatite (HA) ceramic component of artificial hip joints with the bisphosphonates clodronate (C) and pamidronate (P) has been proposed as a means to minimise osteolysis and thereby prevent loosening of the implant. However, the effect of the bisphosphonate coating on bacterial adhesion to the HA materials must be determined before this approach can be implemented.
    LanguageEnglish
    Title of host publicationTransactions of the 25th Annual Meeting of the Society for Biomaterials
    Publication statusPublished - 2001

    Fingerprint

    pamidronate
    Diphosphonates
    Durapatite
    Osteoblasts
    Clodronic Acid
    Bacterial Adhesion
    Osteolysis
    Hip Joint
    Ceramics

    Keywords

    • bisphosphonate-coated hydroxyapatite
    • osteoblasts
    • biotechnology

    Cite this

    Ganguli, A., Lloyd, A. W., Meikle, S. T., & Grant, M. H. (2001). The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts. In Transactions of the 25th Annual Meeting of the Society for Biomaterials
    Ganguli, A. ; Lloyd, A.W. ; Meikle, S.T. ; Grant, M.H. / The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts. Transactions of the 25th Annual Meeting of the Society for Biomaterials. 2001.
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    title = "The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts",
    abstract = "Coating of the hydroxyapatite (HA) ceramic component of artificial hip joints with the bisphosphonates clodronate (C) and pamidronate (P) has been proposed as a means to minimise osteolysis and thereby prevent loosening of the implant. However, the effect of the bisphosphonate coating on bacterial adhesion to the HA materials must be determined before this approach can be implemented.",
    keywords = "bisphosphonate-coated hydroxyapatite, osteoblasts, biotechnology",
    author = "A. Ganguli and A.W. Lloyd and S.T. Meikle and M.H. Grant",
    note = "Ganguli1, A., Henderson, C., Grant, M.H., Meikle, T. The interactions of bisphosphonates in solution and as coatings on hydroxyapatite with osteoblasts. Journal of Materials Science: Materials in Medicine, Volume 13, Number 10 October, 2002",
    year = "2001",
    language = "English",
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    Ganguli, A, Lloyd, AW, Meikle, ST & Grant, MH 2001, The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts. in Transactions of the 25th Annual Meeting of the Society for Biomaterials.

    The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts. / Ganguli, A.; Lloyd, A.W.; Meikle, S.T.; Grant, M.H.

    Transactions of the 25th Annual Meeting of the Society for Biomaterials. 2001.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    TY - CHAP

    T1 - The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts

    AU - Ganguli, A.

    AU - Lloyd, A.W.

    AU - Meikle, S.T.

    AU - Grant, M.H.

    N1 - Ganguli1, A., Henderson, C., Grant, M.H., Meikle, T. The interactions of bisphosphonates in solution and as coatings on hydroxyapatite with osteoblasts. Journal of Materials Science: Materials in Medicine, Volume 13, Number 10 October, 2002

    PY - 2001

    Y1 - 2001

    N2 - Coating of the hydroxyapatite (HA) ceramic component of artificial hip joints with the bisphosphonates clodronate (C) and pamidronate (P) has been proposed as a means to minimise osteolysis and thereby prevent loosening of the implant. However, the effect of the bisphosphonate coating on bacterial adhesion to the HA materials must be determined before this approach can be implemented.

    AB - Coating of the hydroxyapatite (HA) ceramic component of artificial hip joints with the bisphosphonates clodronate (C) and pamidronate (P) has been proposed as a means to minimise osteolysis and thereby prevent loosening of the implant. However, the effect of the bisphosphonate coating on bacterial adhesion to the HA materials must be determined before this approach can be implemented.

    KW - bisphosphonate-coated hydroxyapatite

    KW - osteoblasts

    KW - biotechnology

    UR - http://dx.doi.org/10.1023/A:1019892109411

    UR - http://www.esbiomaterials.eu/main/index.php

    UR - http://www.biomaterials.org/

    M3 - Chapter

    SN - 8024572001

    BT - Transactions of the 25th Annual Meeting of the Society for Biomaterials

    ER -

    Ganguli A, Lloyd AW, Meikle ST, Grant MH. The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts. In Transactions of the 25th Annual Meeting of the Society for Biomaterials. 2001