The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.
- aloe vera
- pro-inflammatory cytokines
Ferro, V. A., Habeeb, F., Stables, G., Bradbury, F., nong, S., Cameron, P., & Plevin, R. J. (2007). The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells. Methods, 42(4), 388-393. https://doi.org/10.1016/j.ymeth.2007.03.005