The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells

V.A. Ferro; F. Habeeb; Graham Stables; F. Bradbury; S. nong; P. Cameron; R.J. Plevin

doi:10.1016/j.ymeth.2007.03.005

The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells

V.A. Ferro, F. Habeeb, Graham Stables, F. Bradbury, S. nong, P. Cameron, R.J. Plevin

Research output: Contribution to journal › Article › peer-review

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Abstract

The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.

Original language	English
Pages (from-to)	388-393
Number of pages	6
Journal	Methods
Volume	42
Issue number	4
DOIs	https://doi.org/10.1016/j.ymeth.2007.03.005
Publication status	Published - 2007

Keywords

aloe vera
anti-inflammatory
inflammation
pro-inflammatory cytokines

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ymeth.2007.03.005

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title = "The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells",

abstract = "The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.",

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T1 - The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells

AU - Ferro, V.A.

AU - Habeeb, F.

AU - Stables, Graham

AU - Bradbury, F.

AU - nong, S.

AU - Cameron, P.

AU - Plevin, R.J.

PY - 2007

Y1 - 2007

N2 - The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.

AB - The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.

KW - aloe vera

KW - anti-inflammatory

KW - inflammation

KW - pro-inflammatory cytokines

U2 - 10.1016/j.ymeth.2007.03.005

DO - 10.1016/j.ymeth.2007.03.005

M3 - Article

SN - 1046-2023

VL - 42

SP - 388

EP - 393

JO - Methods

JF - Methods

IS - 4

ER -

The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells

Abstract

Keywords

UN SDGs

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