The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells

V.A. Ferro, F. Habeeb, Graham Stables, F. Bradbury, S. nong, P. Cameron, R.J. Plevin

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.
Original languageEnglish
Pages (from-to)388-393
Number of pages6
JournalMethods
Volume42
Issue number4
DOIs
Publication statusPublished - 2007

Keywords

  • aloe vera
  • anti-inflammatory
  • inflammation
  • pro-inflammatory cytokines

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