Abstract
The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.
Original language | English |
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Pages (from-to) | 388-393 |
Number of pages | 6 |
Journal | Methods |
Volume | 42 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2007 |
Keywords
- aloe vera
- anti-inflammatory
- inflammation
- pro-inflammatory cytokines