Abstract
| Language | English |
|---|---|
| Number of pages | 11 |
| Journal | Chemistry - A European Journal |
| Early online date | 19 Jun 2018 |
| DOIs | |
| Publication status | E-pub ahead of print - 19 Jun 2018 |
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Keywords
- sustainable chemistry
- polar organometallics
- deep eutectic solvents
- water chemistry
- solvent effects
Cite this
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The future of polar organometallic chemistry written in bio-based solvents and water. / García-Álvarez, Joaquín; Hevia, Eva; Capriati, Vito.
In: Chemistry - A European Journal, 19.06.2018.Research output: Contribution to journal › Review article
TY - JOUR
T1 - The future of polar organometallic chemistry written in bio-based solvents and water
AU - García-Álvarez, Joaquín
AU - Hevia, Eva
AU - Capriati, Vito
N1 - This is the peer reviewed version of the following article: García-Álvarez, J, Hevia, E & Capriati, V 2018, 'The future of polar organometallic chemistry written in bio-based solvents and water' Chemistry - A European Journal. , which has been published in final form at https://doi.org/10.1002/chem.201802873. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
PY - 2018/6/19
Y1 - 2018/6/19
N2 - There is a strong imperative to reduce the release of volatile organic compounds (VOCs) into the environment, and many efforts are currently being made to replace conventional hazardous VOCs in favour of safe, green and bio-renewable reaction media that are not based on crude petroleum. Recent ground-breaking studies from a few laboratories worldwide have shown that both Grignard and (functionalised) organolithium reagents, traditionally handled under strict exclusion of air and humidity and in anhydrous VOCs, can smoothly promote both nucleophilic additions to unsaturated substrates and nucleophilic substitutions in water and other bio-based solvents (glycerol, deep eutectic solvents), competitively with protonolysis, at room temperature and under air. The chemistry of polar organometallics in the above protic media is a complex phenomenon influenced by several factors, and understanding its foundational character is surely stimulating in the perspective of the development of a sustainable organometallic chemistry.
AB - There is a strong imperative to reduce the release of volatile organic compounds (VOCs) into the environment, and many efforts are currently being made to replace conventional hazardous VOCs in favour of safe, green and bio-renewable reaction media that are not based on crude petroleum. Recent ground-breaking studies from a few laboratories worldwide have shown that both Grignard and (functionalised) organolithium reagents, traditionally handled under strict exclusion of air and humidity and in anhydrous VOCs, can smoothly promote both nucleophilic additions to unsaturated substrates and nucleophilic substitutions in water and other bio-based solvents (glycerol, deep eutectic solvents), competitively with protonolysis, at room temperature and under air. The chemistry of polar organometallics in the above protic media is a complex phenomenon influenced by several factors, and understanding its foundational character is surely stimulating in the perspective of the development of a sustainable organometallic chemistry.
KW - sustainable chemistry
KW - polar organometallics
KW - deep eutectic solvents
KW - water chemistry
KW - solvent effects
UR - https://onlinelibrary.wiley.com/journal/15213765
U2 - 10.1002/chem.201802873
DO - 10.1002/chem.201802873
M3 - Review article
JO - Chemistry - A European Journal
T2 - Chemistry - A European Journal
JF - Chemistry - A European Journal
SN - 0947-6539
ER -