The effects of imputing the missing standard deviations on the standard error of meta analysis estimates

N.R.N. Idris, C. Robertson

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A common problem in the meta analysis of continuous data is that some studies do not report sufficient information to calculate the standard deviation (SDs) of the treatment effect. One of the approaches in handling this problem is through imputation. This article examines the empirical implications of imputing the missing SDs on the standard error (SE) of the overall meta analysis estimate. The simulation results show that if the SDs are missing under Missing Completely at Random and Missing at Random mechanism, imputation is recommended. With non random missing, imputation can lead to overestimation of the SE of the estimate.
Original languageEnglish
Pages (from-to)513-526
Number of pages13
JournalCommunications in Statistics - Simulation and Computation
Volume38
Issue number3
DOIs
Publication statusPublished - 2009

Keywords

  • imputation
  • MCAR
  • meta analysis
  • missing SDs
  • standard error

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