The effect of temperature and solvation on the ultrafast dynamics of n-methylacetamide

N.T. Hunt, K. Wynne

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The ultrafast dynamics of N-methylacetamide (NMA), a peptide-linkage model compound, are reported for the first time as a function of temperature and dilution. The rotational-diffusive timescale of NMA was observed to behave in a manner inconsistent with established hydrodynamic theory for simple liquids, exhibiting sharp decreases at elevated temperatures and low concentrations. These were associated with non-stoichiometric changes in far-infrared and terahertz Raman transition strengths. The data is consistent with a model in which neat NMA forms hydrogen bonded aggregates, featuring cooperative effects upon the polarizability and dipole moment that are disrupted by increased temperature or decreased NMA mole fraction.
Original languageEnglish
Pages (from-to)155-159
Number of pages4
JournalChemical Physics Letters
Volume431
DOIs
Publication statusPublished - 2006

Keywords

  • N-methylacetamide
  • (NMA)
  • physics
  • solvation

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