The effect of sodium chloride on poly-L-glutamate conformation

Maxim V. Fedorov, Jonathan M. Goodman, Stephan Schumm

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

A large-scale fully-atomistic molecular dynamics simulation of poly-L-glutamate demonstrates that a small amount of sodium chloride switches the preferred conformation from an extended conformation to a compact alpha-helix.

Original languageEnglish
Pages (from-to)896-898
Number of pages3
JournalChemical Communications
Issue number8
DOIs
Publication statusPublished - 2009

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Keywords

  • coil-helix transition
  • molecular dynamics
  • aqueous solutions
  • acid derivatives
  • alpha-helix
  • multifunctional vectors
  • ionic strength

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