The effect of sodium chloride on poly-L-glutamate conformation

Maxim V. Fedorov, Jonathan M. Goodman, Stephan Schumm

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A large-scale fully-atomistic molecular dynamics simulation of poly-L-glutamate demonstrates that a small amount of sodium chloride switches the preferred conformation from an extended conformation to a compact alpha-helix.

LanguageEnglish
Pages896-898
Number of pages3
JournalChemical Communications
Issue number8
DOIs
Publication statusPublished - 2009

Fingerprint

Sodium chloride
Sodium Chloride
Conformations
Glutamic Acid
Molecular dynamics
Switches
Computer simulation

Keywords

  • coil-helix transition
  • molecular dynamics
  • aqueous solutions
  • acid derivatives
  • alpha-helix
  • multifunctional vectors
  • ionic strength

Cite this

Fedorov, Maxim V. ; Goodman, Jonathan M. ; Schumm, Stephan. / The effect of sodium chloride on poly-L-glutamate conformation. In: Chemical Communications. 2009 ; No. 8. pp. 896-898.
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The effect of sodium chloride on poly-L-glutamate conformation. / Fedorov, Maxim V.; Goodman, Jonathan M.; Schumm, Stephan.

In: Chemical Communications, No. 8, 2009, p. 896-898.

Research output: Contribution to journalArticle

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AU - Goodman, Jonathan M.

AU - Schumm, Stephan

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KW - molecular dynamics

KW - aqueous solutions

KW - acid derivatives

KW - alpha-helix

KW - multifunctional vectors

KW - ionic strength

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