The effect of cell ingrowth on the mechanical behaviour of anchored collagen gels

Research output: Contribution to journalMeeting abstract

Abstract

Collagen gels are often used in studies of cell-matrix interactions and as scaffolds for tissue engineering. However, the effect of cell proliferation on their bulk mechanical properties is still poorly understood. We recently published a method for extracting meaningful mechanical properties from collagen gels of > 99.5% water, using confined compression and biphasic theory (J Biomech 46 (2013) 837). In the present study we used this technique to investigate the effects of cell ingrowth on the transient mechanical behaviour of highly hydrated collagen gels.
Original languageEnglish
Article numberO106
Pages (from-to)567
JournalInternational Journal of Artificial Organs
Volume36
Issue number8
DOIs
Publication statusPublished - Aug 2013
EventXL Congress of the European Society for Artificial Organs - Glasgow, United Kingdom
Duration: 11 Sep 201314 Sep 2013

Keywords

  • cell ingrowth
  • collagen gels
  • cell-matrix interactions
  • tissue engineering scaffolds
  • tissue engineering

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