The effect of branching on the one- and two-photon absorption, cell viability and localization of cationic triarylborane chromophores with dipolar vs. octupolar charge distributions for cellular imaging

Stefanie Griesbeck, Evripidis Michail, Florian Rauch, Hiroaki Ogasawara, Chenguang Wang, Yoshikatsu Sato, Robert Edkins, Zuolun Zhang, Masayasu Taki, Christoph Lambert, Shigehiro Yamaguchi, Todd B. Marder

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12 Citations (Scopus)
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Abstract

Two different chromophores, namely a dipolar and an octupolar system, were prepared and their linear and non-linear optical properties as well as their bioimaging capabilities were compared. Both contain triphenylamine as the donor and a triarylborane as the acceptor, the latter modified with cationic trimethylammonio groups to provide solubility in aqueous media. The octupolar system exhibits a much higher two-photon brightness, and also better cell viability and enhanced selectivity for lysosomes compared with the dipolar chromophore. Furthermore, both dyes were applied in two-photon excited fluorescence (TPEF) live-cell imaging.
Original languageEnglish
Pages (from-to)13164-13175
Number of pages12
JournalChemistry - A European Journal
Volume25
Issue number57
Early online date19 Jul 2019
DOIs
Publication statusPublished - 11 Oct 2019

Keywords

  • borane
  • fluorescence
  • two-photon excited fluorescence
  • cell imaging
  • lysosome

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    • 12 Citations
    • 1 Article

    Water-soluble triarylborane chromophores for one- and two-photon excited fluorescence imaging of mitochondria in cells

    Griesbeck, S., Zhang, Z., Gutmann, M., Lühmann, T., Edkins, R. M., Clermont, G., Lazar, A. N., Haehnel, M., Edkins, K., Eichhorn, A., Blanchard-Desce, M., Meinel, L. & Marder, T. B., 4 Oct 2016, In : Chemistry - A European Journal . 22, 41, p. 14701-14706 6 p.

    Research output: Contribution to journalArticle

  • 37 Citations (Scopus)

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