Abstract
| Language | English |
|---|---|
| Journal | Chemistry - A European Journal |
| Early online date | 19 Jul 2019 |
| DOIs | |
| Publication status | E-pub ahead of print - 19 Jul 2019 |
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Keywords
- borane
- fluorescence
- two-photon excited fluorescence
- cell imaging
- lysosome
Cite this
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The effect of branching on the one- and two-photon absorption, cell viability and localization of cationic triarylborane chromophores with dipolar vs. octupolar charge distributions for cellular imaging. / Griesbeck, Stefanie; Michail, Evripidis; Rauch, Florian; Ogasawara, Hiroaki; Wang, Chenguang; Sato, Yoshikatsu; Edkins, Robert; Zhang, Zuolun; Taki, Masayasu; Lambert, Christoph; Yamaguchi, Shigehiro; Marder, Todd B.
In: Chemistry - A European Journal, 19.07.2019.Research output: Contribution to journal › Article
TY - JOUR
T1 - The effect of branching on the one- and two-photon absorption, cell viability and localization of cationic triarylborane chromophores with dipolar vs. octupolar charge distributions for cellular imaging
AU - Griesbeck, Stefanie
AU - Michail, Evripidis
AU - Rauch, Florian
AU - Ogasawara, Hiroaki
AU - Wang, Chenguang
AU - Sato, Yoshikatsu
AU - Edkins, Robert
AU - Zhang, Zuolun
AU - Taki, Masayasu
AU - Lambert, Christoph
AU - Yamaguchi, Shigehiro
AU - Marder, Todd B.
PY - 2019/7/19
Y1 - 2019/7/19
N2 - Two different chromophores, namely a dipolar and an octupolar system, were prepared and their linear and non-linear optical properties as well as their bioimaging capabilities were compared. Both contain triphenylamine as the donor and a triarylborane as the acceptor, the latter modified with cationic trimethylammonio groups to provide solubility in aqueous media. The octupolar system exhibits a much higher two-photon brightness, and also better cell viability and enhanced selectivity for lysosomes compared with the dipolar chromophore. Furthermore, both dyes were applied in two-photon excited fluorescence (TPEF) live-cell imaging.
AB - Two different chromophores, namely a dipolar and an octupolar system, were prepared and their linear and non-linear optical properties as well as their bioimaging capabilities were compared. Both contain triphenylamine as the donor and a triarylborane as the acceptor, the latter modified with cationic trimethylammonio groups to provide solubility in aqueous media. The octupolar system exhibits a much higher two-photon brightness, and also better cell viability and enhanced selectivity for lysosomes compared with the dipolar chromophore. Furthermore, both dyes were applied in two-photon excited fluorescence (TPEF) live-cell imaging.
KW - borane
KW - fluorescence
KW - two-photon excited fluorescence
KW - cell imaging
KW - lysosome
UR - https://onlinelibrary.wiley.com/journal/15213765
U2 - 10.1002/chem.201902461
DO - 10.1002/chem.201902461
M3 - Article
JO - Chemistry - A European Journal
T2 - Chemistry - A European Journal
JF - Chemistry - A European Journal
SN - 0947-6539
ER -