The drug discovery portal: a computational platform for identifying drug leads from academia

Rachel Clark; Blair Johnston; Simon Mackay; Catherine Breslin; Murray Robertson; Oliver Brook Sutcliffe; Mark Dufton; Alan Harvey

doi:10.2174/138161210791164018

The drug discovery portal: a computational platform for identifying drug leads from academia

Rachel Clark, Blair Johnston, Simon Mackay, Catherine Breslin, Murray Robertson, Oliver Brook Sutcliffe, Mark Dufton, Alan Harvey

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

The Drug Discovery Portal (DDP) is a research initiative based at the University of Strathclyde in Glasgow, Scotland. It was initiated in 2007 by a group of researchers with expertise in virtual screening. Academic research groups in the university working in drug discovery programmes estimated there was a historical collection of physical compounds going back 50 years that had never been adequately catalogued. This invaluable resource has been harnessed to form the basis of the DDP library, and has attracted a highpercentage uptake from universities and research groups internationally. Its unique attributes include the diversity of the academic database, sourced from synthetic, medicinal and phytochemists working in academic laboratories and the ability to link biologists with appropriate chemical expertise through a target-matching virtual screening approach, and it has resulted in seven emerging hit development programmes between international contributors

Original language	English
Pages (from-to)	1697-1702
Number of pages	6
Journal	Current Pharmaceutical Design
Volume	16
Issue number	15
DOIs	https://doi.org/10.2174/138161210791164018
Publication status	Published - May 2010

Keywords

virtual screening
academic drug discovery
natural products
chemical diversity
high-throughput
strategies
in-silico
chemical libraries

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10.2174/138161210791164018

SMSdrug.net: Alignment Of Synthesis, Medicinal Chemistry And Strucrural Genomics To Accelerate Uk Drug Discovery: Network SMS-Drug
Tomkinson, N. (Principal Investigator), C. Bagley, M. (Academic), Feilden, H. (Academic), Johnston, B. (Academic), Knapp, S. (Academic), MacKay, S. (Academic), Overington, J. (Academic) & Spencer, J. (Academic)
EPSRC (Engineering and Physical Sciences Research Council)
1/09/11 → 31/08/15
Project: Research

Cite this

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title = "The drug discovery portal: a computational platform for identifying drug leads from academia",

abstract = "The Drug Discovery Portal (DDP) is a research initiative based at the University of Strathclyde in Glasgow, Scotland. It was initiated in 2007 by a group of researchers with expertise in virtual screening. Academic research groups in the university working in drug discovery programmes estimated there was a historical collection of physical compounds going back 50 years that had never been adequately catalogued. This invaluable resource has been harnessed to form the basis of the DDP library, and has attracted a highpercentage uptake from universities and research groups internationally. Its unique attributes include the diversity of the academic database, sourced from synthetic, medicinal and phytochemists working in academic laboratories and the ability to link biologists with appropriate chemical expertise through a target-matching virtual screening approach, and it has resulted in seven emerging hit development programmes between international contributors",

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author = "Rachel Clark and Blair Johnston and Simon Mackay and Catherine Breslin and Murray Robertson and Sutcliffe, {Oliver Brook} and Mark Dufton and Alan Harvey",

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AU - Dufton, Mark

AU - Harvey, Alan

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The drug discovery portal: a computational platform for identifying drug leads from academia

Abstract

Keywords

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Projects

SMSdrug.net: Alignment Of Synthesis, Medicinal Chemistry And Strucrural Genomics To Accelerate Uk Drug Discovery: Network SMS-Drug

Cite this