The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.
- cellular response
- polyurethane surface
- vascular extracellular matrix proteins
- vascular graft
Smith, K. H., Jozwiak, A. B., Bax, D. V., Kielty, C. M., & Black, R. A. (2007). The cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft. Tissue Engineering, 13(7), 1762. https://doi.org/10.1089/ten.2007.1501