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The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung
F Burns, I W Rodger, N J Pyne
Strathclyde Institute Of Pharmacy And Biomedical Sciences
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Article
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peer-review
73
Citations (Scopus)
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Medicine & Life Sciences
Cyclic AMP-Dependent Protein Kinase Catalytic Subunits
100%
Cyclic GMP
72%
Phosphoric Diester Hydrolases
72%
Guinea Pigs
54%
zaprinast
39%
Hydrolysis
34%
Lung
33%
Phosphodiesterase Inhibitors
30%
Cyclic AMP-Dependent Protein Kinases
25%
Isoenzymes
24%
Inhibitory Concentration 50
22%
Type 5 Cyclic Nucleotide Phosphodiesterases
18%
Phosphorylation
17%
Kinetics
9%
Enzymes
6%
Chemical Compounds
Vmax
45%
Hydrolysis
38%
Phosphodiesterase V Inhibitor
32%
EC 3.1.4.* (Phosphoric Diester Hydrolase) Inhibitor
31%
Protein
25%
% Inhibition
23%