The application of tribology in assessing texture perception of oral liquid medicines

Hannah Batchelor, Rebecca Venables, John Marriott, Tom Mills

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The palatability of medicines is likely to have a significant impact on patient adherence and consequently, on the safety and efficacy of a medicinal product. Palatability encompasses properties of medicines not limited to taste including swallowability (e.g. size, shape, texture). However, there has been limited work undertaken to measure the texture of medicines and how this may affect palatability and subsequent adherence. Tribology offers an understanding of oral processes and can allow physical properties of materials to be linked to "mouthfeel". This paper describes a preliminary application of tribology to oral liquid medicines and demonstrates that this technique is useful in the development of future oral liquid medicines.

Original languageEnglish
Pages (from-to)277-281
Number of pages5
JournalInternational Journal of Pharmaceutics
Volume479
Issue number2
DOIs
Publication statusPublished - 20 Feb 2015

Keywords

  • mouthfeel/nedicine
  • texture
  • tribology

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