TY - CONF
T1 - The application of micro-plate dynamics on monitoring cell property
AU - Ma, Xianghong
AU - Wu, Zhangming
N1 - [1] DR Basel, GU Lee, KM Hansen, LA Chrisey and RJ Colton, "A high-sensitivity micromachined biosensor", Biosensors and Bioelectronics, Volume 12, Issue 8, 1997, Page iv.
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[3] Passian, A. Muralidharan, G; Mehta, A; Simpson, H; Ferrell, TL; Thundat, T. "Manipulation of microcantilever oscillations", Ultramicroscopy, v 97, n 1-4, October/November, 2003, p 391-399.
[4] Lobontiu, Nicolae, Garcia, Ephrahim, "Two microcantilever designs: Lumped-parameter model for static and modal analysis", Journal of Microelectromechanical Systems, v 13, n 1, February, 2004, p 41-50.
PY - 2008/12/2
Y1 - 2008/12/2
N2 - The paper presents a novel biosensing method of monitoring cell properties using the information derived from the dynamics of micro-scale plates. Micro cantilevers have been widely applied as mechanical biosensors. In dynamic sense, cantilever is considered as 1 dimensional whereas plate is a 2 dimensional structure. In this paper we provide the first analytical solution to the dynamics of distributed mass loaded microplate in submerged fluid. In a further step, we propose to derive the dynamical infomation of the micro plate and use it to infer the spatial information of the cells when monitoring the cell growth on the plate.
AB - The paper presents a novel biosensing method of monitoring cell properties using the information derived from the dynamics of micro-scale plates. Micro cantilevers have been widely applied as mechanical biosensors. In dynamic sense, cantilever is considered as 1 dimensional whereas plate is a 2 dimensional structure. In this paper we provide the first analytical solution to the dynamics of distributed mass loaded microplate in submerged fluid. In a further step, we propose to derive the dynamical infomation of the micro plate and use it to infer the spatial information of the cells when monitoring the cell growth on the plate.
KW - micro plate
KW - biosensor technology
KW - cell property
UR - http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=4749527
M3 - Paper
SP - 169
EP - 172
T2 - 15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008
Y2 - 2 December 2008 through 4 December 2008
ER -