The application of micro-plate dynamics on monitoring cell property

Xianghong Ma, Zhangming Wu

Research output: Contribution to conferencePaper

Abstract

The paper presents a novel biosensing method of monitoring cell properties using the information derived from the dynamics of micro-scale plates. Micro cantilevers have been widely applied as mechanical biosensors. In dynamic sense, cantilever is considered as 1 dimensional whereas plate is a 2 dimensional structure. In this paper we provide the first analytical solution to the dynamics of distributed mass loaded microplate in submerged fluid. In a further step, we propose to derive the dynamical infomation of the micro plate and use it to infer the spatial information of the cells when monitoring the cell growth on the plate.

Conference

Conference15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008
CountryNew Zealand
CityAuckland
Period2/12/084/12/08

Fingerprint

Growth Plate
Biosensing Techniques

Keywords

  • micro plate
  • biosensor technology
  • cell property

Cite this

Ma, X., & Wu, Z. (2008). The application of micro-plate dynamics on monitoring cell property. 169-172. Paper presented at 15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008, Auckland, New Zealand.
Ma, Xianghong ; Wu, Zhangming. / The application of micro-plate dynamics on monitoring cell property. Paper presented at 15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008, Auckland, New Zealand.4 p.
@conference{6024883e7eef467fae3fb43ce023dca0,
title = "The application of micro-plate dynamics on monitoring cell property",
abstract = "The paper presents a novel biosensing method of monitoring cell properties using the information derived from the dynamics of micro-scale plates. Micro cantilevers have been widely applied as mechanical biosensors. In dynamic sense, cantilever is considered as 1 dimensional whereas plate is a 2 dimensional structure. In this paper we provide the first analytical solution to the dynamics of distributed mass loaded microplate in submerged fluid. In a further step, we propose to derive the dynamical infomation of the micro plate and use it to infer the spatial information of the cells when monitoring the cell growth on the plate.",
keywords = "micro plate, biosensor technology, cell property",
author = "Xianghong Ma and Zhangming Wu",
note = "[1] DR Basel, GU Lee, KM Hansen, LA Chrisey and RJ Colton, {"}A high-sensitivity micromachined biosensor{"}, Biosensors and Bioelectronics, Volume 12, Issue 8, 1997, Page iv. {2] Fritz, J; Baller, MK; Lang, HP; Rothuizen, H; Vettiger, P; Meyer, E; G{\"u}ntherodt, H; Gerber, C; Gimzewski, JK, {"}Translating biomolecular recognition into nanomechanics{"} Science, Volume 288, Issue 5464, April 14, 2000, Pages 316-318. [3] Passian, A. Muralidharan, G; Mehta, A; Simpson, H; Ferrell, TL; Thundat, T. {"}Manipulation of microcantilever oscillations{"}, Ultramicroscopy, v 97, n 1-4, October/November, 2003, p 391-399. [4] Lobontiu, Nicolae, Garcia, Ephrahim, {"}Two microcantilever designs: Lumped-parameter model for static and modal analysis{"}, Journal of Microelectromechanical Systems, v 13, n 1, February, 2004, p 41-50. ; 15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008 ; Conference date: 02-12-2008 Through 04-12-2008",
year = "2008",
month = "12",
day = "2",
language = "English",
pages = "169--172",

}

Ma, X & Wu, Z 2008, 'The application of micro-plate dynamics on monitoring cell property' Paper presented at 15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008, Auckland, New Zealand, 2/12/08 - 4/12/08, pp. 169-172.

The application of micro-plate dynamics on monitoring cell property. / Ma, Xianghong; Wu, Zhangming.

2008. 169-172 Paper presented at 15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008, Auckland, New Zealand.

Research output: Contribution to conferencePaper

TY - CONF

T1 - The application of micro-plate dynamics on monitoring cell property

AU - Ma, Xianghong

AU - Wu, Zhangming

N1 - [1] DR Basel, GU Lee, KM Hansen, LA Chrisey and RJ Colton, "A high-sensitivity micromachined biosensor", Biosensors and Bioelectronics, Volume 12, Issue 8, 1997, Page iv. {2] Fritz, J; Baller, MK; Lang, HP; Rothuizen, H; Vettiger, P; Meyer, E; Güntherodt, H; Gerber, C; Gimzewski, JK, "Translating biomolecular recognition into nanomechanics" Science, Volume 288, Issue 5464, April 14, 2000, Pages 316-318. [3] Passian, A. Muralidharan, G; Mehta, A; Simpson, H; Ferrell, TL; Thundat, T. "Manipulation of microcantilever oscillations", Ultramicroscopy, v 97, n 1-4, October/November, 2003, p 391-399. [4] Lobontiu, Nicolae, Garcia, Ephrahim, "Two microcantilever designs: Lumped-parameter model for static and modal analysis", Journal of Microelectromechanical Systems, v 13, n 1, February, 2004, p 41-50.

PY - 2008/12/2

Y1 - 2008/12/2

N2 - The paper presents a novel biosensing method of monitoring cell properties using the information derived from the dynamics of micro-scale plates. Micro cantilevers have been widely applied as mechanical biosensors. In dynamic sense, cantilever is considered as 1 dimensional whereas plate is a 2 dimensional structure. In this paper we provide the first analytical solution to the dynamics of distributed mass loaded microplate in submerged fluid. In a further step, we propose to derive the dynamical infomation of the micro plate and use it to infer the spatial information of the cells when monitoring the cell growth on the plate.

AB - The paper presents a novel biosensing method of monitoring cell properties using the information derived from the dynamics of micro-scale plates. Micro cantilevers have been widely applied as mechanical biosensors. In dynamic sense, cantilever is considered as 1 dimensional whereas plate is a 2 dimensional structure. In this paper we provide the first analytical solution to the dynamics of distributed mass loaded microplate in submerged fluid. In a further step, we propose to derive the dynamical infomation of the micro plate and use it to infer the spatial information of the cells when monitoring the cell growth on the plate.

KW - micro plate

KW - biosensor technology

KW - cell property

UR - http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=4749527

M3 - Paper

SP - 169

EP - 172

ER -

Ma X, Wu Z. The application of micro-plate dynamics on monitoring cell property. 2008. Paper presented at 15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008, Auckland, New Zealand.